| Literature DB >> 205079 |
Abstract
Intracerebral inoculation of avian sarcoma virus (ASV) in postnatal animals induces gliomas and sarcomas but no neuronal tumors. High titer Bratislava-77 strain ASV was inoculated intracerebrally in fetal F-344 rats between 17 and 20 days of gestation: a time of active neuronal proliferation. Following birth inoculated rats developed gliomas and sarcomas but no neuronal tumors. The results are evidence that the glial-mesenchymal tropism of in vivo ASV neuro-oncogenesis is independent of stage of neurocytodifferentiation at inoculation.Entities:
Mesh:
Year: 1978 PMID: 205079 DOI: 10.1007/bf00689552
Source DB: PubMed Journal: Acta Neuropathol ISSN: 0001-6322 Impact factor: 17.088