Literature DB >> 6277141

The localization of glial fibrillary acidic protein in brain tumors induced in hamsters with avian sarcoma virus.

Y Nakazato, H Yamaguchi, K Takahashi, Y Ishida.   

Abstract

The immunohistochemical localization of glial fibrillary acidic protein (GFAP) was studied by the peroxidase-antiperoxidase (PAP) method in avian sarcoma virus (ASV)-induced brain tumors in hamsters. One hundred twenty-four tumors including 54 astrocytomas, 64 pleomorphic gliomas, five sarcomas, and one unclassified tumor were stained with anti-GFAP serum. A positive immunostaining was seen in astrocytomas and in pleomorphic gliomas. Sarcomas and an unclassified tumor were negative. These results confirmed that a majority of ASV-induced brain tumors contained neoplastic glial cells, and further suggested that the astrocyte is a main target cell of ASV in the experimental neuro-oncogenesis.

Entities:  

Mesh：

Substances：

Year:  1981        PMID： 6277141     DOI： 10.1007/bf00690993

Source DB:  PubMed          Journal:  Acta Neuropathol        ISSN： 0001-6322            Impact factor:   17.088


  17 in total

1.  The topographical distribution of S-100 and GFA proteins in the adult rat brain: an immunohistochemical study using horseradish peroxidase-labelled antibodies.

Authors:  S K Ludwin; J C Kosek; L F Eng
Journal:  J Comp Neurol       Date:  1976-01-15       Impact factor: 3.215

2.  BRAIN TUMOURS INDUCED IN HAMSTERS INOCULATED INTRACEREBRALLY AT BIRTH WITH ROUS SARCOMA VIRUS.

Authors:  G F RABOTTI; W A RAINE
Journal:  Nature       Date:  1964-11-28       Impact factor: 49.962

3.  Contribution of immunohistochemistry to diagnostic problems of human cerebral tumors.

Authors:  L F Eng; L J Rubinstein
Journal:  J Histochem Cytochem       Date:  1978-07       Impact factor: 2.479

4.  Astrocyte-specific protein and neuroglial differentiation. An immunofluorescence study with antibodies to the glial fibrillary acidic protein.

Authors:  A Bignami; D Dahl
Journal:  J Comp Neurol       Date:  1974-01-01       Impact factor: 3.215

5.  Brain tumor types induced by the Schmidt-Ruppin strain of Rous sarcoma virus in inbred Fischer rats.

Authors:  R F Wilfong; D D Bigner; D J Self; W Wechsler
Journal:  Acta Neuropathol       Date:  1973       Impact factor: 17.088

6.  Morphologic observations of brain tumors in PD4 hamsters induced by four strains of avian sarcoma virus.

Authors:  P C Burger; D D Bigner; D J Self
Journal:  Acta Neuropathol       Date:  1973       Impact factor: 17.088

7.  [Studies on the immunohistochemical localization of S-100 and glial fibrillary acidic proteins in the rat nervous system and in human brain tumors (author's transl)].

Authors:  H Yamaguchi
Journal:  No To Shinkei       Date:  1980-10

8.  Glial fibrillary acidic protein in giant cell tumors of brain and other gliomas. A possible relationship to malignancy, differentiation, and pleomorphism of glia.

Authors:  P E Duffy; Y Y Huang; M M Rapport; L Graf
Journal:  Acta Neuropathol       Date:  1980       Impact factor: 17.088

9.  The fine structure of intracranial neoplasms induced by the inoculation of avian sarcoma virus in neonatal and adult rats.

Authors:  D D Copeland; F A Talley; D D Bigner
Journal:  Am J Pathol       Date:  1976-04       Impact factor: 4.307

10.  Ultrastructural localization of glial fibrillary acidic protein in mouse cerebellum by immunoperoxidase labeling.

Authors:  M Schachner; E T Hedley-Whyte; D W Hsu; G Schoonmaker; A Bignami
Journal:  J Cell Biol       Date:  1977-10       Impact factor: 10.539
View more
  1 in total

1.  Immunohistochemical study of glial fibrillary acidic protein in avian sarcoma virus-induced gliomas in dogs.

Authors:  R H Britt; B E Lyons; L F Eng; S H Bigner; D D Bigner
Journal:  J Neurooncol       Date:  1985       Impact factor: 4.130
  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.