Literature DB >> 2050723

Alcohol use and burn injury.

J D Jones1, B Barber, L Engrav, D Heimbach.   

Abstract

Charts of 108 consecutive adult patients with flame burns of 20% to 70% total body surface area were reviewed to determine the incidence of acute alcohol intoxication and the likelihood that intoxicated patients were chronic alcohol abusers, to assess morbidity and mortality in the alcoholic patient with burns, and to characterize the intervention used in postdischarge treatment of the alcoholic patient with burns who survives. Twenty-seven percent of patients were acutely intoxicated at the time of injury. Evidence for chronic alcohol abuse was apparent in 90% of intoxicated patients, compared to only 11% of nonintoxicated patients (p = 0.0001). Alcoholic patients with burns not only had an overall mortality rate three times that of nonalcoholics (p = 0.001) but also died of smaller burns (p less than 0.05). Surviving alcoholic patients with burns required significantly more intravenous antibiotics and a longer hospitalization. Social service evaluation of use of alcohol was made in 84% of the cases of surviving intoxicated burn victims. Further intervention was undertaken in two thirds of these cases, usually involving an outpatient treatment program.

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Year:  1991        PMID: 2050723     DOI: 10.1097/00004630-199103000-00012

Source DB:  PubMed          Journal:  J Burn Care Rehabil        ISSN: 0273-8481


  24 in total

1.  Alteration in intestine tight junction protein phosphorylation and apoptosis is associated with increase in IL-18 levels following alcohol intoxication and burn injury.

Authors:  Xiaoling Li; Suhail Akhtar; Mashkoor A Choudhry
Journal:  Biochim Biophys Acta       Date:  2011-10-07

2.  Dysregulation of microRNA biogenesis in the small intestine after ethanol and burn injury.

Authors:  Niya L Morris; Adam M Hammer; Abigail R Cannon; Robin C Gagnon; Xiaoling Li; Mashkoor A Choudhry
Journal:  Biochim Biophys Acta Mol Basis Dis       Date:  2017-04-09       Impact factor: 5.187

Review 3.  A role for corticosterone in impaired intestinal immunity and barrier function in a rodent model of acute alcohol intoxication and burn injury.

Authors:  Mashkoor A Choudhry; Xiaoling Li; Irshad H Chaudry
Journal:  J Neuroimmune Pharmacol       Date:  2006-12       Impact factor: 4.147

4.  Did changes in minimum age drinking laws affect adolescent drowning (1970-90)?

Authors:  J Howland; J Birckmayer; D Hemenway; J Cote
Journal:  Inj Prev       Date:  1998-12       Impact factor: 2.399

5.  Examining the Impact of Psychological Factors on Hospital Length of Stay for Burn Survivors: A Systematic Review.

Authors:  Kyle H O'Brien; Victor Lushin
Journal:  J Burn Care Res       Date:  2019-01-01       Impact factor: 1.845

Review 6.  In vitro and in vivo models of acute alcohol exposure.

Authors:  Angela Dolganiuc; Gyongyi Szabo
Journal:  World J Gastroenterol       Date:  2009-03-14       Impact factor: 5.742

7.  Heme oxygenase-1 protects against neutrophil-mediated intestinal damage by down-regulation of neutrophil p47phox and p67phox activity and O2- production in a two-hit model of alcohol intoxication and burn injury.

Authors:  Xiaoling Li; Martin G Schwacha; Irshad H Chaudry; Mashkoor A Choudhry
Journal:  J Immunol       Date:  2008-05-15       Impact factor: 5.422

8.  Assault and substance abuse characterize burn injuries in homeless patients.

Authors:  C Bradley Kramer; Nicole S Gibran; David M Heimbach; Frederick P Rivara; Matthew B Klein
Journal:  J Burn Care Res       Date:  2008 May-Jun       Impact factor: 1.845

9.  Alcohol, burn injury, and the intestine.

Authors:  Mashkoor A Choudhry; Irshad H Chaudry
Journal:  J Emerg Trauma Shock       Date:  2008-07

10.  Implications of alcohol intoxication at the time of burn and smoke inhalation injury: an epidemiologic and clinical analysis.

Authors:  Christopher S Davis; Thomas J Esposito; Anna G Palladino-Davis; Karen Rychlik; Carol R Schermer; Richard L Gamelli; Elizabeth J Kovacs
Journal:  J Burn Care Res       Date:  2013 Jan-Feb       Impact factor: 1.845

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