Literature DB >> 20503979

Xestosaprols from the Indonesian marine sponge Xestospongia sp.

Jingqiu Dai1, Analia Sorribas, Wesley Y Yoshida, Michelle Kelly, Philip G Williams.   

Abstract

Eight pentacyclic compounds, xestosaprols F-M (1-8), were isolated from a marine sponge belonging to the genus Xestospongia. The structures of these new compounds were determined on the basis of extensive analyses of NMR experiments and mass spectrometric measurements. These compounds inhibited the aspartic protease BACE1 at moderate levels in a dose-dependent manner.

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Year:  2010        PMID： 20503979      PMCID： PMC3152581          DOI： 10.1021/np100203x

Source DB:  PubMed          Journal:  J Nat Prod        ISSN： 0163-3864            Impact factor:   4.050


  2 in total

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Journal:  Bioorg Med Chem       Date:  2005-02-15       Impact factor: 3.641

2.  Beta galactosidase enzyme fragment complementation as a high-throughput screening protease technology.

Authors:  Tabassum Naqvi; Anice Lim; Riaz Rouhani; Raj Singh; Richard M Eglen
Journal:  J Biomol Screen       Date:  2004-08
  2 in total
  9 in total

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2.  Isolation and structures of axistatins 1-3 from the Republic of Palau marine sponge Agelas axifera Hentschel .

Authors:  George R Pettit; Yuping Tang; Qingwen Zhang; Gregory T Bourne; Christoph A Arm; John E Leet; John C Knight; Robin K Pettit; Jean-Charles Chapuis; Dennis L Doubek; Franklin J Ward; Christine Weber; John N A Hooper
Journal:  J Nat Prod       Date:  2013-02-14       Impact factor: 4.050

Review 3.  Recent progress in neuroactive marine natural products.

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Journal:  Mar Drugs       Date:  2015-04-28       Impact factor: 5.118

5.  Bioactive marine drugs and marine biomaterials for brain diseases.

Authors:  Clara Grosso; Patrícia Valentão; Federico Ferreres; Paula B Andrade
Journal:  Mar Drugs       Date:  2014-05-02       Impact factor: 5.118

Review 6.  Benefits under the Sea: The Role of Marine Compounds in Neurodegenerative Disorders.

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Journal:  Mar Drugs       Date:  2021-01-08       Impact factor: 5.118

Review 7.  Marine-Derived Compounds with Anti-Alzheimer's Disease Activities.

Authors:  Salar Hafez Ghoran; Anake Kijjoa
Journal:  Mar Drugs       Date:  2021-07-24       Impact factor: 5.118

Review 8.  Marine sponge derived natural products between 2001 and 2010: trends and opportunities for discovery of bioactives.

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Review 9.  Collective Locomotion of Human Cells, Wound Healing and Their Control by Extracts and Isolated Compounds from Marine Invertebrates.

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Journal:  Molecules       Date:  2020-05-26       Impact factor: 4.411
  9 in total

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