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Literature DB >> 20499142

microRNAs and EMT in mammary cells and breast cancer.

Josephine A Wright¹, Jennifer K Richer, Gregory J Goodall.

Abstract

MicroRNAs are master regulators of gene expression in many biological and pathological processes, including mammary gland development and breast cancer. The differentiation program termed the epithelial to mesenchymal transition (EMT) involves changes in a number of microRNAs. Some of these microRNAs have been shown to control cellular plasticity through the suppression of EMT-inducers or to influence cellular phenotype through the suppression of genes involved in defining the epithelial and mesenchymal cell states. This has led to the suggestion that microRNAs maybe a novel therapeutic target for the treatment of breast cancer. In this review, we will discuss microRNAs that are involved in EMT in mammary cells and breast cancer.

Entities: Disease

Mesh：

Substances：

Year: 2010 PMID： 20499142 DOI： 10.1007/s10911-010-9183-z

Source DB: PubMed Journal: J Mammary Gland Biol Neoplasia ISSN： 1083-3021 Impact factor: 2.673

136 in total

1. MicroRNA genes are transcribed by RNA polymerase II.

Authors: Yoontae Lee; Minju Kim; Jinju Han; Kyu-Hyun Yeom; Sanghyuk Lee; Sung Hee Baek; V Narry Kim
Journal: EMBO J Date: 2004-09-16 Impact factor: 11.598

2. Downregulation of miRNA-200c links breast cancer stem cells with normal stem cells.

Authors: Yohei Shimono; Maider Zabala; Robert W Cho; Neethan Lobo; Piero Dalerba; Dalong Qian; Maximilian Diehn; Huiping Liu; Sarita P Panula; Eric Chiao; Frederick M Dirbas; George Somlo; Renee A Reijo Pera; Kaiqin Lao; Michael F Clarke
Journal: Cell Date: 2009-08-07 Impact factor: 41.582

Review 3. Keeping abreast of the mammary epithelial hierarchy and breast tumorigenesis.

Authors: Jane E Visvader
Journal: Genes Dev Date: 2009-11-15 Impact factor: 11.361

4. miR-200a-mediated downregulation of ZEB2 and CTNNB1 differentially inhibits nasopharyngeal carcinoma cell growth, migration and invasion.

Authors: Hongping Xia; Samuel S Ng; Songshan Jiang; William K C Cheung; Johnny Sze; Xiu-Wu Bian; Hsiang-Fu Kung; Marie C Lin
Journal: Biochem Biophys Res Commun Date: 2009-11-24 Impact factor: 3.575

5. A genetic screen implicates miRNA-372 and miRNA-373 as oncogenes in testicular germ cell tumors.

Authors: P Mathijs Voorhoeve; Carlos le Sage; Mariette Schrier; Ad J M Gillis; Hans Stoop; Remco Nagel; Ying-Poi Liu; Josyanne van Duijse; Jarno Drost; Alexander Griekspoor; Eitan Zlotorynski; Norikazu Yabuta; Gabriella De Vita; Hiroshi Nojima; Leendert H J Looijenga; Reuven Agami
Journal: Cell Date: 2006-03-24 Impact factor: 41.582

6. A microRNA, miR-101a, controls mammary gland development by regulating cyclooxygenase-2 expression.

Authors: Tetsuya Tanaka; Shingo Haneda; Kazuhiko Imakawa; Senkiti Sakai; Kentaro Nagaoka
Journal: Differentiation Date: 2008-11-20 Impact factor: 3.880

7. miR-206 Expression is down-regulated in estrogen receptor alpha-positive human breast cancer.

Authors: Naoto Kondo; Tatsuya Toyama; Hiroshi Sugiura; Yoshitaka Fujii; Hiroko Yamashita
Journal: Cancer Res Date: 2008-07-01 Impact factor: 12.701

8. MicroRNAs modulate the chemosensitivity of tumor cells.

Authors: Paul E Blower; Ji-Hyun Chung; Joseph S Verducci; Shili Lin; Jong-Kook Park; Zunyan Dai; Chang-Gong Liu; Thomas D Schmittgen; William C Reinhold; Carlo M Croce; John N Weinstein; Wolfgang Sadee
Journal: Mol Cancer Ther Date: 2008-01-09 Impact factor: 6.261

9. Epithelial to mesenchymal transition predicts gefitinib resistance in cell lines of head and neck squamous cell carcinoma and non-small cell lung carcinoma.

Authors: Barbara A Frederick; Barbara A Helfrich; Christopher D Coldren; Di Zheng; Dan Chan; Paul A Bunn; David Raben
Journal: Mol Cancer Ther Date: 2007-05-31 Impact factor: 6.261

10. miR-200 enhances mouse breast cancer cell colonization to form distant metastases.

Authors: Derek M Dykxhoorn; Yichao Wu; Huangming Xie; Fengyan Yu; Ashish Lal; Fabio Petrocca; Denis Martinvalet; Erwei Song; Bing Lim; Judy Lieberman
Journal: PLoS One Date: 2009-09-29 Impact factor: 3.240

29 in total

Review 1. Emerging role of microRNAs in drug-resistant breast cancer.

Authors: Sarmila Majumder; Samson T Jacob
Journal: Gene Expr Date: 2011

2. Epigenetic inactivation of miR-203 as a key step in neural crest epithelial-to-mesenchymal transition.

Authors: Estefanía Sánchez-Vásquez; Marianne E Bronner; Pablo H Strobl-Mazzulla
Journal: Development Date: 2019-04-11 Impact factor: 6.868

Review 3. Connecting the dots: chromatin and alternative splicing in EMT.

Authors: Jessica A Warns; James R Davie; Archana Dhasarathy
Journal: Biochem Cell Biol Date: 2015-07-07 Impact factor: 3.626

4. γ-Tocotrienol reversal of epithelial-to-mesenchymal transition in human breast cancer cells is associated with inhibition of canonical Wnt signalling.

Authors: R A Ahmed; O A Alawin; P W Sylvester
Journal: Cell Prolif Date: 2016-06-21 Impact factor: 6.831

5. MicroRNAs in pancreatic ductal adenocarcinoma.

Authors: Jong Y Park; James Helm; Domenico Coppola; Donghwa Kim; Mokenge Malafa; Seung Joon Kim
Journal: World J Gastroenterol Date: 2011-02-21 Impact factor: 5.742

6. Effects of SDF-1-CXCR4 signaling on microRNA expression and tumorigenesis in estrogen receptor-alpha (ER-α)-positive breast cancer cells.

Authors: Lyndsay V Rhodes; Melyssa R Bratton; Yun Zhu; Syreeta L Tilghman; Shannon E Muir; Virgilio A Salvo; Chandra R Tate; Steven Elliott; Kenneth P Nephew; Bridgette M Collins-Burow; Matthew E Burow
Journal: Exp Cell Res Date: 2011-08-30 Impact factor: 3.905

7. Computational identification and characterization of novel microRNA in the mammary gland of dairy goat (Capra hircus).

Authors: Bo Qu; Youwen Qiu; Zhen Zhen; Feng Zhao; Chunmei Wang; Yingjun Cui; Qizhang Li; Li Zhang
Journal: J Genet Date: 2016-09 Impact factor: 1.166