| Literature DB >> 20498315 |
Giuseppe Valenza1, Biju Joseph, Johannes Elias, Heike Claus, Anett Oesterlein, Kathrin Engelhardt, Doris Turnwald, Matthias Frosch, Marianne Abele-Horn, Christoph Schoen.
Abstract
A total of 489 clinical isolates of Pseudomonas aeruginosa was investigated for metallo-beta-lactamase (MBL) production. Molecular analysis detected a blaVIM-1 gene in the chromosome of one isolate and a blaVIM-2 gene carried on the plasmid in seven isolates. Moreover, we showed that an initial screening by combined susceptibility testing of imipenem and ceftazidime followed by a confirmatory EDTA combination disk test represents a valid alternative to the molecular investigation of MBL genes, making MBL detection possible in routine diagnostic laboratories.Entities:
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Year: 2010 PMID: 20498315 PMCID: PMC2916321 DOI: 10.1128/AAC.00080-10
Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN: 0066-4804 Impact factor: 5.191