Literature DB >> 20491049

Treatment of keratoconus with Ferrara ICRS and consideration of the efficacy of the Ferrara nomogram in a 5-year follow-up.

Paolo Maria Pesando1, Maria Pia Ghiringhello, Giuseppe Di Meglio, Salvatore Romeo.   

Abstract

PURPOSE: To investigate Ferrara intrastromal ring segments (FIRS) as a therapeutic opportunity to treat keratoconus (KC), to reduce the necessity for cornea transplant, and to improve quality of vision of patients with this disease. We demonstrate that the procedure is safe, reversible, and reliable, and can delay/stop the KC progression.
METHODS: A total of 130 eyes of 83 patients with KC, intolerant to contact lenses, implanted with FIRS were considered. Average follow-up was 37 months with a minimum of 2 years and a maximum of 5 years. For all patients, manifest refraction, uncorrected visual acuity (UCVA), best-corrected visual acuity (BCVA) corneal map, Orbscan, and intraoperative pachymetry were performed and were compared to postoperative measurements.
RESULTS: A total of 93.84% (122 patients) of the eyes gained lines of UCVA and only 1.53% (2 eyes) lost them. A total of 97.69% (127 patients) of the treated eyes gained lines of BCVA and no eyes lost them. The value of K1 and K2 were considerably reduced over 5 years. The preoperative value of K average of 49.27 D became 4.68 D postoperatively. Both the UCVA and the BCVA showed an increase. The UCVA changed from 0.14 lines preoperatively to 0.32 postoperatively while the BCVA changed from 0.40 to 0.59. The spherical equivalent changed from -8.34 D before the operation to -2.83 D after the operation.
CONCLUSIONS: FIRS make KC cornea more regular and the patients have increased corrected and uncorrected visual acuity postoperatively. The progression of KC was stopped and the cornea thickness minimally, but regularly, improved.

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Year:  2010        PMID: 20491049     DOI: 10.1177/112067211002000509

Source DB:  PubMed          Journal:  Eur J Ophthalmol        ISSN: 1120-6721            Impact factor:   2.597


  5 in total

1.  Clinical outcomes after intrastromal corneal ring segments reoperation in keratoconus patients.

Authors:  Leonardo Torquetti; Guilherme Ferrara; Franklin Almeida; Leandro Cunha; Paulo Ferrara; Jesús Merayo-Lloves
Journal:  Int J Ophthalmol       Date:  2013-12-18       Impact factor: 1.779

2.  Bevel toric multicurve rigid gas-permeable lens for keratoconus.

Authors:  Ryoji Yanai; Kiichi Ueda; Koh-Hei Sonoda
Journal:  Jpn J Ophthalmol       Date:  2012-12-07       Impact factor: 2.447

3.  Photorefractive keratectomy in patients with mild to moderate stable keratoconus: a five-year prospective follow-up study.

Authors:  Elias Chelala; Hala El Rami; Ali Dirani; Ali Fadlallah; Omar Fakhoury; Elias Warrak
Journal:  Clin Ophthalmol       Date:  2013-09-26

Review 4.  Intrastromal corneal ring segments: how successful is the surgical treatment of keratoconus?

Authors:  Jorge L Alio; Alfredo Vega-Estrada; Santiago Esperanza; Rafael I Barraquer; Miguel A Teus; Joaquim Murta
Journal:  Middle East Afr J Ophthalmol       Date:  2014 Jan-Mar

5.  Implantation of intracorneal ring segments in pediatric patients: long-term follow-up.

Authors:  Ana Carolina Abreu; Luisa Malheiro; João Coelho; Miguel Mesquita Neves; Miguel Gomes; Luis Oliveira; Pedro Menéres
Journal:  Int Med Case Rep J       Date:  2018-02-07
  5 in total

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