PURPOSE OF REVIEW: Study of the variability of the cortical mantle thickness is now a key issue in neuroimaging. Here we describe a more recent trend aiming at the study of the variability of the cortical folding morphology. RECENT FINDINGS: Computerized three-dimensional versions of gyrification index and other morphometric features dedicated to the folding patterns are modified in psychiatric syndromes and neurologic disorders. These observations provide new insights into the mechanisms involved in abnormal development or abnormal aging. SUMMARY: Quantification of the folding morphology will contribute to the global endeavor aiming at building biomarkers from neuroimaging data, with a specific focus on developmental diseases.
PURPOSE OF REVIEW: Study of the variability of the cortical mantle thickness is now a key issue in neuroimaging. Here we describe a more recent trend aiming at the study of the variability of the cortical folding morphology. RECENT FINDINGS: Computerized three-dimensional versions of gyrification index and other morphometric features dedicated to the folding patterns are modified in psychiatric syndromes and neurologic disorders. These observations provide new insights into the mechanisms involved in abnormal development or abnormal aging. SUMMARY: Quantification of the folding morphology will contribute to the global endeavor aiming at building biomarkers from neuroimaging data, with a specific focus on developmental diseases.
Authors: Marie Schaer; Meritxell Bach Cuadra; Nick Schmansky; Bruce Fischl; Jean-Philippe Thiran; Stephan Eliez Journal: J Vis Exp Date: 2012-01-02 Impact factor: 1.355
Authors: Peter Savadjiev; Yogesh Rathi; Sylvain Bouix; Alex R Smith; Robert T Schultz; Ragini Verma; Carl-Fredrik Westin Journal: Med Image Anal Date: 2014-07-08 Impact factor: 8.545
Authors: Kiho Im; Rudolph Pienaar; Michael J Paldino; Nadine Gaab; Albert M Galaburda; P Ellen Grant Journal: Cereb Cortex Date: 2012-09-17 Impact factor: 5.357
Authors: Maureen Dennis; Brenda J Spiegler; Jenifer J Juranek; Erin D Bigler; O Carter Snead; Jack M Fletcher Journal: Neurosci Biobehav Rev Date: 2013-10-03 Impact factor: 8.989