Literature DB >> 20485078

Use of dermal regeneration template (Integra) for reconstruction of full-thickness complex oncologic scalp defects.

Muhammad A A Khan1, Syed N Ali, Mohammed Farid, Megha Pancholi, Sukh Rayatt, Lok H Yap.   

Abstract

The reconstruction of full-thickness scalp defects remains a surgical challenge. Different types of reconstruction had varying success including the use of dermal regeneration template (DRT). We reviewed the surgical outcome of 30 patients who underwent application of DRT for resurfacing of full-thickness scalp defects when the pericranium was excised and the outer cortex of the calvarial bone was burred after the excision of scalp neoplasm. This was a retrospective review of 30 patients who had scalp reconstruction with DRT undertaken by the senior author between October 2004 and June 2007. The mean age of patients in our series was 63 years (37-91 years). There were 14 men and 16 women. The indications for re-excision and DRT reconstruction in 28 patients were close margins and aggressive tumor type, whereas 2 patients had a recurrence. The mean defect size was 95 cm2 (16-275 cm2). The second stage of the reconstruction occurred on postoperative day 42 (postoperative days 27-62). The mean follow-up period was 14 months. Two patients had minor complications. For both stages, the combined average operative time was 128 minutes. The use of DRT is a rung of the reconstructive ladder that deserves consideration. In our series of 30 patients who required secondary reconstruction of complex scalp defects, the use of DRT has been seen to provide safe and durable soft-tissue cover for full-thickness scalp defects. The reduced operative time and inpatient stay are desirable characteristics particularly in elderly patients with multiple comorbidities.

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Year:  2010        PMID: 20485078     DOI: 10.1097/SCS.0b013e3181d8418e

Source DB:  PubMed          Journal:  J Craniofac Surg        ISSN: 1049-2275            Impact factor:   1.046


  9 in total

1.  [Giant squamous cell carcinoma of the scalp: successful excision with use of bovine dermal substitute].

Authors:  M Zutt; S Ischebeck; K M Kaune
Journal:  Hautarzt       Date:  2013-12       Impact factor: 0.751

2.  Giant tricholemmal squamous cell carcinoma with cranial infiltration.

Authors:  Uwe Wollina; Yousef Bayyoud; Thomas Kittner; Eberhard Dürig
Journal:  J Clin Aesthet Dermatol       Date:  2011-04

Review 3.  Technical Refinements with the Use of Biologic Healing Agents.

Authors:  Rami P Dibbs; Monal Depani; James F Thornton
Journal:  Semin Plast Surg       Date:  2022-02-25       Impact factor: 2.195

Review 4.  Skin cancers and dermal substitutes: Is it safe? Review of the literature and presentation of a 2-stage surgical protocol for the treatment of non-melanoma skin cancers of the head in fragile patients.

Authors:  Marco Marcasciano; Marco Mazzocchi; Juste Kaciulyte; Noemi Spissu; Donato Casella; Diego Ribuffo; Luca Andrea Dessy
Journal:  Int Wound J       Date:  2018-06-04       Impact factor: 3.315

5.  Evaluation of lymphangiogenesis in acellular dermal matrix.

Authors:  Mario Cherubino; Igor Pellegatta; Federico Tamborini; Michele Cerati; Fausto Sessa; Luigi Valdatta
Journal:  Indian J Plast Surg       Date:  2014 Sep-Dec

Review 6.  Multifocal cutaneous angiosarcoma of the scalp-A challenging reconstructive case managed with skin substitutes.

Authors:  Henrique Messias; Mariluz Martins; Carlos Zagalo; Pedro Gomes
Journal:  Cancer Rep (Hoboken)       Date:  2022-07-12

7.  One-Stage Reconstruction of Scalp after Full-Thickness Oncologic Defects Using a Dermal Regeneration Template (Integra).

Authors:  Barbara De Angelis; Pietro Gentile; Eleonora Tati; Davide J Bottini; Ilaria Bocchini; Fabrizio Orlandi; Giampiero Pepe; Chiara Di Segni; Giulio Cervelli; Valerio Cervelli
Journal:  Biomed Res Int       Date:  2015-11-16       Impact factor: 3.411

8.  The Use of Integra Dermal Regeneration Template Versus Flaps for Reconstruction of Full-Thickness Scalp Defects Involving the Calvaria: A Cost-Benefit Analysis.

Authors:  M Schiavon; M Francescon; D Drigo; G Salloum; R Baraziol; J Tesei; E Fraccalanza; F Barbone
Journal:  Aesthetic Plast Surg       Date:  2016-10-03       Impact factor: 2.326

9.  Integra-based Reconstruction of Large Scalp Wounds: A Case Report and Systematic Review of the Literature.

Authors:  Maxwell B Johnson; Alex K Wong
Journal:  Plast Reconstr Surg Glob Open       Date:  2016-10-24
  9 in total

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