| Literature DB >> 20483436 |
Yongmei Hu1, Fanny C F Ip, Guangmiao Fu, Haihong Pang, Wencai Ye, Nancy Y Ip.
Abstract
Dammarane-type saponins (1-7), together with five known compounds, were isolated from the aerial parts of Gynostemma pentaphyllum. Compounds 1-4, 6 and 7 induced the phosphorylation of ERK protein in primary rat cortical neurons, which indicates their potential neuroactivity. On the other hand, no induction of ERK phosphorylation was observed for HEK293 cells following treatment with saponins 1, 3, 4 and 7. 2010 Elsevier Ltd. All rights reserved.Entities:
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Year: 2010 PMID： 20483436 DOI： 10.1016/j.phytochem.2010.04.003
Source DB: PubMed Journal: Phytochemistry ISSN： 0031-9422 Impact factor: 4.072