Literature DB >> 20483412

Simulation of pulmonary air flow with a subject-specific boundary condition.

Youbing Yin1, Jiwoong Choi, Eric A Hoffman, Merryn H Tawhai, Ching-Long Lin.   

Abstract

We present a novel image-based technique to estimate a subject-specific boundary condition (BC) for computational fluid dynamics (CFD) simulation of pulmonary air flow. The information of regional ventilation for an individual is derived by registering two computed tomography (CT) lung datasets and then passed to the CT-resolved airways as the flow BC. The CFD simulations show that the proposed method predicts lobar volume changes consistent with direct image-measured metrics, whereas the other two traditional BCs (uniform velocity or uniform pressure) yield lobar volume changes and regional pressure differences inconsistent with observed physiology. Copyright 2010 Elsevier Ltd. All rights reserved.

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Year:  2010        PMID： 20483412      PMCID： PMC3034656          DOI： 10.1016/j.jbiomech.2010.03.048

Source DB:  PubMed          Journal:  J Biomech        ISSN： 0021-9290            Impact factor:   2.712


  28 in total

1.  Characteristics of the turbulent laryngeal jet and its effect on airflow in the human intra-thoracic airways.

Authors:  Ching-Long Lin; Merryn H Tawhai; Geoffrey McLennan; Eric A Hoffman
Journal:  Respir Physiol Neurobiol       Date:  2007-02-14       Impact factor: 1.931

2.  Tracking lung tissue motion and expansion/compression with inverse consistent image registration and spirometry.

Authors:  Gary E Christensen; Joo Hyun Song; Wei Lu; Issam El Naqa; Daniel A Low
Journal:  Med Phys       Date:  2007-06       Impact factor: 4.071

3.  CFD simulation of aerosol deposition in an anatomically based human large-medium airway model.

Authors:  Baoshun Ma; Kenneth R Lutchen
Journal:  Ann Biomed Eng       Date:  2008-12-12       Impact factor: 3.934

4.  Registration-based estimates of local lung tissue expansion compared to xenon CT measures of specific ventilation.

Authors:  Joseph M Reinhardt; Kai Ding; Kunlin Cao; Gary E Christensen; Eric A Hoffman; Shalmali V Bodas
Journal:  Med Image Anal       Date:  2008-04-12       Impact factor: 8.545

5.  Evaluation of lobar biomechanics during respiration using image registration.

Authors:  Kai Ding; Youbing Yin; Kunlin Cao; Gary E Christensen; Ching-Long Lin; Eric A Hoffman; Joseph M Reinhardt
Journal:  Med Image Comput Comput Assist Interv       Date:  2009

6.  Effect of low-xenon and krypton supplementation on signal/noise of regional CT-based ventilation measurements.

Authors:  Deokiee Chon; Kenneth C Beck; Brett A Simon; Hidenori Shikata; Osama I Saba; Eric A Hoffman
Journal:  J Appl Physiol (1985)       Date:  2006-11-22

7.  Flow analyses in the lower airways: patient-specific model and boundary conditions.

Authors:  J W De Backer; W G Vos; C D Gorlé; P Germonpré; B Partoens; F L Wuyts; P M Parizel; W De Backer
Journal:  Med Eng Phys       Date:  2007-12-21       Impact factor: 2.242

8.  The effects of geometry on airflow in the acinar region of the human lung.

Authors:  Haribalan Kumar; Merryn H Tawhai; Eric A Hoffman; Ching-Long Lin
Journal:  J Biomech       Date:  2009-05-31       Impact factor: 2.712

9.  Characterization of the interstitial lung diseases via density-based and texture-based analysis of computed tomography images of lung structure and function.

Authors:  Eric A Hoffman; Joseph M Reinhardt; Milan Sonka; Brett A Simon; Junfeng Guo; Osama Saba; Deokiee Chon; Shaher Samrah; Hidenori Shikata; Juerg Tschirren; Kalman Palagyi; Kenneth C Beck; Geoffrey McLennan
Journal:  Acad Radiol       Date:  2003-10       Impact factor: 3.173

10.  CT-measured regional specific volume change reflects regional ventilation in supine sheep.

Authors:  Matthew K Fuld; R Blaine Easley; Osama I Saba; Deokiee Chon; Joseph M Reinhardt; Eric A Hoffman; Brett A Simon
Journal:  J Appl Physiol (1985)       Date:  2008-02-07
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  54 in total

1.  Comparing MDI and DPI aerosol deposition using in vitro experiments and a new stochastic individual path (SIP) model of the conducting airways.

Authors:  P Worth Longest; Geng Tian; Ross L Walenga; Michael Hindle
Journal:  Pharm Res       Date:  2012-06       Impact factor: 4.200

2.  Assessment of regional non-linear tissue deformation and air volume change of human lungs via image registration.

Authors:  Nariman Jahani; Youbing Yin; Eric A Hoffman; Ching-Long Lin
Journal:  J Biomech       Date:  2014-03-13       Impact factor: 2.712

3.  Assessment of regional ventilation and deformation using 4D-CT imaging for healthy human lungs during tidal breathing.

Authors:  Nariman Jahani; Sanghun Choi; Jiwoong Choi; Krishna Iyer; Eric A Hoffman; Ching-Long Lin
Journal:  J Appl Physiol (1985)       Date:  2015-08-27

4.  Lung lobar slippage assessed with the aid of image registration.

Authors:  Youbing Yin; Eric A Hoffman; Ching-Long Lin
Journal:  Med Image Comput Comput Assist Interv       Date:  2010

5.  Registration-based assessment of regional lung function via volumetric CT images of normal subjects vs. severe asthmatics.

Authors:  Sanghun Choi; Eric A Hoffman; Sally E Wenzel; Merryn H Tawhai; Youbing Yin; Mario Castro; Ching-Long Lin
Journal:  J Appl Physiol (1985)       Date:  2013-06-06

6.  Comparison of image registration based measures of regional lung ventilation from dynamic spiral CT with Xe-CT.

Authors:  Kai Ding; Kunlin Cao; Matthew K Fuld; Kaifang Du; Gary E Christensen; Eric A Hoffman; Joseph M Reinhardt
Journal:  Med Phys       Date:  2012-08       Impact factor: 4.071

7.  Computational modeling of airway and pulmonary vascular structure and function: development of a "lung physiome".

Authors:  Merryn Tawhai; A Clark; G Donovan; K Burrowes
Journal:  Crit Rev Biomed Eng       Date:  2011

8.  Numerical simulations of aerosol delivery to the human lung with an idealized laryngeal model, image-based airway model, and automatic meshing algorithm.

Authors:  Shinjiro Miyawaki; Eric A Hoffman; Ching-Long Lin
Journal:  Comput Fluids       Date:  2017-02-10       Impact factor: 3.013

9.  Effects of CT resolution and radiodensity threshold on the CFD evaluation of nasal airflow.

Authors:  Maurizio Quadrio; Carlotta Pipolo; Stefano Corti; Francesco Messina; Chiara Pesci; Alberto M Saibene; Samuele Zampini; Giovanni Felisati
Journal:  Med Biol Eng Comput       Date:  2015-06-10       Impact factor: 2.602

10.  Differences in Particle Deposition Between Members of Imaging-Based Asthma Clusters.

Authors:  Jiwoong Choi; Lawrence J LeBlanc; Sanghun Choi; Babak Haghighi; Eric A Hoffman; Patrick O'Shaughnessy; Sally E Wenzel; Mario Castro; Sean Fain; Nizar Jarjour; Mark L Schiebler; Loren Denlinger; Renishkumar Delvadia; Ross Walenga; Andrew Babiskin; Ching-Long Lin
Journal:  J Aerosol Med Pulm Drug Deliv       Date:  2019-03-19       Impact factor: 2.849
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