OBJECTIVES: In this laboratory study, we examined the use of a swept-source optical coherence tomography (SS-OCT) as a diagnostic tool for occlusal caries. METHODS: One-hundred and eleven investigation sites of occlusal fissures were selected from 62 extracted teeth and examined visually using conventional dental equipment without any magnification. SS-OCT observations were carried out on the same locations as where the conventional examination had been performed. The teeth were then sectioned using a diamond saw and directly viewed under a confocal laser scanning microscope (CLSM). Presence and extent of caries was scored in each observation and the obtained results from SS-OCT and conventional visual inspection were compared with the CLSM. The reproducibility and indices of sensitivity and specificity of SS-OCT were calculated and compared with those of the visual inspection. The results were statistically analyzed using receiver operating characteristic (ROC) curve and Spearman rank correlation test. RESULTS: SS-OCT could clearly detect the presence of enamel demineralization lesion in a tomography image synthesized based on the backscatter signal (sensitivity=0.98). Although the sensitivity for dentine caries of SS-OCT was over that of the visual inspection, the detection level was decreased to 0.60. When the methods were compared to the CLSM, the diagnostic accuracy of SS-OCT was better than that of the conventional visual inspection (Az values of visual inspection and SS-OCT, 0.74 versus 0.86 for enamel demineralization, 0.68 versus 0.80 for dentine caries; Spearman's correlation coefficients to CLSM; visual inspection: 0.665, SS-OCT: 0.824). CONCLUSIONS: The carious demineralization, especially in enamel, can be clearly discriminated as a highlighted area due to scattering of light matches the location of demineralized area at the base of the fissure and the results correlated well with the CLSM. Copyright 2010 Elsevier Ltd. All rights reserved.
OBJECTIVES: In this laboratory study, we examined the use of a swept-source optical coherence tomography (SS-OCT) as a diagnostic tool for occlusal caries. METHODS: One-hundred and eleven investigation sites of occlusal fissures were selected from 62 extracted teeth and examined visually using conventional dental equipment without any magnification. SS-OCT observations were carried out on the same locations as where the conventional examination had been performed. The teeth were then sectioned using a diamond saw and directly viewed under a confocal laser scanning microscope (CLSM). Presence and extent of caries was scored in each observation and the obtained results from SS-OCT and conventional visual inspection were compared with the CLSM. The reproducibility and indices of sensitivity and specificity of SS-OCT were calculated and compared with those of the visual inspection. The results were statistically analyzed using receiver operating characteristic (ROC) curve and Spearman rank correlation test. RESULTS: SS-OCT could clearly detect the presence of enamel demineralization lesion in a tomography image synthesized based on the backscatter signal (sensitivity=0.98). Although the sensitivity for dentine caries of SS-OCT was over that of the visual inspection, the detection level was decreased to 0.60. When the methods were compared to the CLSM, the diagnostic accuracy of SS-OCT was better than that of the conventional visual inspection (Az values of visual inspection and SS-OCT, 0.74 versus 0.86 for enamel demineralization, 0.68 versus 0.80 for dentine caries; Spearman's correlation coefficients to CLSM; visual inspection: 0.665, SS-OCT: 0.824). CONCLUSIONS: The carious demineralization, especially in enamel, can be clearly discriminated as a highlighted area due to scattering of light matches the location of demineralized area at the base of the fissure and the results correlated well with the CLSM. Copyright 2010 Elsevier Ltd. All rights reserved.