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Literature DB >> 20467917

Spontaneous complete regression of hepatocellular carcinoma.

Raul E Storey¹, Ana L Huerta, Amir Khan, Damian A Laber.

Abstract

In medical terminology, spontaneous regression of cancer refers to exceptional and unexplained partial or complete disappearance of cancer without medical intervention. This phenomenon has been described in various malignancies with no well established causative factors, except perhaps immune mediated. Here we present a rare case of hepatocellular carcinoma with possible metastasis to the lung by computed tomography with complete regression of both the primary tumor and the pulmonary nodules without medical intervention. Our patient may represent the first case of complete regression of the HCC with possible lung metastasis by computed tomography caused by abstinence from alcohol. This phenomenon was confirmed by surgical resection and pathologic evaluation.

Entities: Chemical Disease Species

Mesh：

Year: 2010 PMID： 20467917 DOI： 10.1007/s12032-010-9562-8

Source DB: PubMed Journal: Med Oncol ISSN： 1357-0560 Impact factor: 3.064

14 in total

1. The role of the immune system in the control of hepatocellular carcinoma.

Authors: James P O'Beirne; Phillip M Harrison
Journal: Eur J Gastroenterol Hepatol Date: 2004-11 Impact factor: 2.566

Review 2. Spontaneous regression of hepatocellular carcinoma: three case reports and a categorized review of the literature.

Authors: Susana Oquiñena; Mercedes Iñarrairaegui; Juan J Vila; Felix Alegre; Jose M Zozaya; Bruno Sangro
Journal: Dig Dis Sci Date: 2008-08-21 Impact factor: 3.199

Review 3. Spontaneous regression of hepatocellular carcinoma: report of a case.

Authors: Hiroshi Ohtani; Osamu Yamazaki; Mitsuharu Matsuyama; Katsuhiko Horii; Sadatoshi Shimizu; Hiroko Oka; Hiroko Nebiki; Kiyohide Kioka; Osamu Kurai; Yasuko Kawasaki; Takao Manabe; Katsuko Murata; Ryoichi Matsuo; Takeshi Inoue
Journal: Surg Today Date: 2005 Impact factor: 2.549

4. Transferable anticancer innate immunity in spontaneous regression/complete resistance mice.

Authors: Amy M Hicks; Gregory Riedlinger; Mark C Willingham; Martha A Alexander-Miller; C Von Kap-Herr; Mark J Pettenati; Anne M Sanders; Holly M Weir; Wei Du; Joseph Kim; Andrew J G Simpson; Lloyd J Old; Zheng Cui
Journal: Proc Natl Acad Sci U S A Date: 2006-05-08 Impact factor: 11.205

Review 5. Complete spontaneous regression of cancer: four case reports, review of literature, and discussion of possible mechanisms involved.

Authors: W Y Chang
Journal: Hawaii Med J Date: 2000-10

6. Spontaneous partial regression of hepatocellular carcinoma in a cirrhotic patient.

Authors: Judith Meza-Junco; Aldo J Montaño-Loza; Braulio Martinez-Benítez; Tatiana Cabrera-Aleksandrova
Journal: Ann Hepatol Date: 2007 Jan-Mar Impact factor: 2.400

7. Spontaneous regression of advanced cancer: identification of a unique genetically determined, age-dependent trait in mice.

Authors: Zheng Cui; Mark C Willingham; Amy M Hicks; Martha A Alexander-Miller; Timothy D Howard; Gregory A Hawkins; Mark S Miller; Holly M Weir; Wei Du; Cynthia J DeLong
Journal: Proc Natl Acad Sci U S A Date: 2003-04-30 Impact factor: 11.205

Review 8. Efforts to explain spontaneous regression of cancer.

Authors: W H Cole
Journal: J Surg Oncol Date: 1981 Impact factor: 3.454

9. The mysterious case of spontaneous disappearance of hepatocellular carcinoma.

Authors: P Del Poggio; M Mattiello; L Gilardoni; C Jamoletti; S Colombo; G Zabbialini
Journal: Dig Liver Dis Date: 2009-07 Impact factor: 4.088

10. Hepatocellular carcinoma with spontaneous regression: report of the rare case.

Authors: Yusuke Arakawa; Hiroki Mori; Toru Ikegami; Jun Hanaoka; Mami Kanamoto; Hirofumi Kanemura; Yuji Morine; Satoru Imura; Mitsuo Shimada
Journal: Hepatogastroenterology Date: 2008 Sep-Oct

9 in total

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Authors: Kyosuke Matsuzaki; Ryoichi Imamura; Toshichika Iwanishi; Masahiro Nakagawa; Go Tanigawa; Koichi Tsutahara; Kohki Shimazu; Hiroaki Fushimi; Toyonori Tsuzuki; Seiji Yamaguchi
Journal: Can Urol Assoc J Date: 2015 Jan-Feb Impact factor: 1.862

Review 2. Spontaneous regression of hepatocellular carcinoma is most often associated with tumour hypoxia or a systemic inflammatory response.

Authors: Jonathan I Huz; Marcovalerio Melis; Umut Sarpel
Journal: HPB (Oxford) Date: 2012-05-15 Impact factor: 3.647

Review 3. Spontaneous Regression of Hepatocellular Carcinoma with Multiple Lung Metastases: A Case Report and Review of the Literature.

Authors: Eirini Pectasides; Rebecca Miksad; Sergey Pyatibrat; Amogh Srivastava; Andrea Bullock
Journal: Dig Dis Sci Date: 2016-04-01 Impact factor: 3.199

4. Management considerations for purported spontaneous regression of hepatocellular carcinoma: a case report.

Authors: Takahide Sasaki; Daisuke Fukumori; Kentaroh Yamamoto; Fumio Yamamoto; Hirotsune Igimi; Yuichi Yamashita
Journal: Case Rep Gastroenterol Date: 2013-03-20

5. Spontaneous massive necrosis of hepatocellular carcinoma with narrowing and occlusion of the arteries and portal veins.

Authors: Takahiro Tomino; Yo-Ichi Yamashita; Tomohiro Iguchi; Shinji Itoh; Mizuki Ninomiya; Toru Ikegami; Tomoharu Yoshizumi; Yuji Soejima; Hirofumi Kawanaka; Tetsuo Ikeda; Shinichi Aishima; Ken Shirabe; Yoshihiko Maehara
Journal: Case Rep Gastroenterol Date: 2014-04-24

6. Spontaneous complete necrosis of hepatocellular carcinoma: A case report and review of the literature.

Authors: Yuki Takeda; Noritaka Wakui; Yasutsugu Asai; Nobuhiro Dan; Yoshiya Yamauchi; Nobuo Ueki; Takafumi Otsuka; Nobuyuki Oba; Shuta Nishinakagawa; Masami Minagawa; Yasushi Takeda; Saori Shiono; Tatsuya Kojima
Journal: Oncol Lett Date: 2015-02-05 Impact factor: 2.967