Literature DB >> 20466907

Research ethics. Beyond access vs. protection in trials of innovative therapies.

Alex John London1, Jonathan Kimmelman, Marina Elena Emborg.   

Abstract

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Year:  2010        PMID： 20466907      PMCID： PMC4516403          DOI： 10.1126/science.1189369

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


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  15 in total

1.  What makes clinical research ethical?

Authors:  E J Emanuel; D Wendler; C Grady
Journal:  JAMA       Date:  2000 May 24-31       Impact factor: 56.272

2.  Cell therapy. Renovating the heart.

Authors:  Jennifer Couzin; Gretchen Vogel
Journal:  Science       Date:  2004-04-09       Impact factor: 47.728

3.  Two dogmas of research ethics and the integrative approach to human-subjects research.

Authors:  Alex John London
Journal:  J Med Philos       Date:  2007 Mar-Apr

4.  Medicine. A history lesson for stem cells.

Authors:  James M Wilson
Journal:  Science       Date:  2009-05-08       Impact factor: 47.728

5.  Geron gets green light for human trial of ES cell-derived product.

Authors:  Joe Alper
Journal:  Nat Biotechnol       Date:  2009-03       Impact factor: 54.908

Review 6.  Comparison of treatment effects between animal experiments and clinical trials: systematic review.

Authors:  Pablo Perel; Ian Roberts; Emily Sena; Philipa Wheble; Catherine Briscoe; Peter Sandercock; Malcolm Macleod; Luciano E Mignini; Pradeep Jayaram; Khalid S Khan
Journal:  BMJ       Date:  2006-12-15

Review 7.  Lost in translation: treatment trials in the SOD1 mouse and in human ALS.

Authors:  Michael Benatar
Journal:  Neurobiol Dis       Date:  2007-01-03       Impact factor: 5.996

8.  Invisible barriers to clinical trials: the impact of structural, infrastructural, and procedural barriers to opening oncology clinical trials.

Authors:  David M Dilts; Alan B Sandler
Journal:  J Clin Oncol       Date:  2006-10-01       Impact factor: 44.544

9.  Why do people cooperate with medical research? Findings from three studies.

Authors:  Mary Dixon-Woods; Carolyn Tarrant
Journal:  Soc Sci Med       Date:  2009-04-24       Impact factor: 4.634

10.  Launching invasive, first-in-human trials against Parkinson's disease: ethical considerations.

Authors:  Jonathan Kimmelman; Alex John London; Bernard Ravina; Tim Ramsay; Mark Bernstein; Alan Fine; Frank W Stahnisch; Marina Elena Emborg
Journal:  Mov Disord       Date:  2009-10-15       Impact factor: 10.338
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  24 in total

1.  How do researchers decide early clinical trials?

Authors:  Hannah Grankvist; Jonathan Kimmelman
Journal:  Med Health Care Philos       Date:  2016-06

2.  Research ethics. Rethinking research ethics: the case of postmarketing trials.

Authors:  Alex John London; Jonathan Kimmelman; Benjamin Carlisle
Journal:  Science       Date:  2012-05-04       Impact factor: 47.728

Review 3.  Ethical development of stem-cell-based interventions.

Authors:  Amanda MacPherson; Jonathan Kimmelman
Journal:  Nat Med       Date:  2019-07-03       Impact factor: 53.440

4.  Ethics, error, and initial trials of efficacy.

Authors:  Spencer Phillips Hey; Jonathan Kimmelman
Journal:  Sci Transl Med       Date:  2013-05-08       Impact factor: 17.956

5.  The risk-escalation model: a principled design strategy for early-phase trials.

Authors:  Spencer Phillips Hey; Jonathan Kimmelman
Journal:  Kennedy Inst Ethics J       Date:  2014-06

Review 6.  Is Participation in Cancer Phase I Trials Really Therapeutic?

Authors:  Jonathan Kimmelman
Journal:  J Clin Oncol       Date:  2016-09-30       Impact factor: 44.544

7.  The ethics of HIV "cure" research: what can we learn from consent forms?

Authors:  Gail E Henderson
Journal:  AIDS Res Hum Retroviruses       Date:  2015-01       Impact factor: 2.205

Review 8.  Do we still need human embryonic stem cells for stem cell-based therapies? Epistemic and ethical aspects.

Authors:  Kristina Hug; Göran Hermerén
Journal:  Stem Cell Rev Rep       Date:  2011-11       Impact factor: 5.739

Review 9.  Ethical considerations in tissue engineering research: Case studies in translation.

Authors:  Hannah B Baker; John P McQuilling; Nancy M P King
Journal:  Methods       Date:  2015-08-14       Impact factor: 3.608

10.  Building an ethical foundation for first-in-human nanotrials.

Authors:  Rebecca Dresser
Journal:  J Law Med Ethics       Date:  2012       Impact factor: 1.718
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