OBJECTIVE: To investigate the diagnostic value of brief cognitive tests in differentiating vascular dementia (VaD) from Alzheimer's disease (AD). METHOD: Fifteen patients with mild VaD, 15 patients with mild probable AD and 30 healthy controls, matched for age, education and dementia severity, were submitted to the following cognitive tests: clock drawing (free drawing and copy), category and letter fluency, delayed recall test of figures and the EXIT 25 battery. RESULTS: VaD patients performed worse than AD patients in category fluency (p=0.014), letter fluency (p=0.043) and CLOX 2 (p=0.023), while AD cases performed worse than VaD patients in delayed recall (p=0.013). However, ROC curves for these tests displayed low sensitivity and specificity for the differential diagnosis between VaD and AD. CONCLUSION: Although the performance of VaD and AD patients was significantly different in some cognitive tests, the value of such instruments in differentiating VaD from AD proved to be very limited.
OBJECTIVE: To investigate the diagnostic value of brief cognitive tests in differentiating vascular dementia (VaD) from Alzheimer's disease (AD). METHOD: Fifteen patients with mild VaD, 15 patients with mild probable AD and 30 healthy controls, matched for age, education and dementia severity, were submitted to the following cognitive tests: clock drawing (free drawing and copy), category and letter fluency, delayed recall test of figures and the EXIT 25 battery. RESULTS: VaD patients performed worse than ADpatients in category fluency (p=0.014), letter fluency (p=0.043) and CLOX 2 (p=0.023), while AD cases performed worse than VaD patients in delayed recall (p=0.013). However, ROC curves for these tests displayed low sensitivity and specificity for the differential diagnosis between VaD and AD. CONCLUSION: Although the performance of VaD and ADpatients was significantly different in some cognitive tests, the value of such instruments in differentiating VaD from AD proved to be very limited.
Authors: Gali H Weissberger; Jessica V Strong; Kayla B Stefanidis; Mathew J Summers; Mark W Bondi; Nikki H Stricker Journal: Neuropsychol Rev Date: 2017-09-22 Impact factor: 7.444
Authors: Eliasz Engelhardt; Carla Tocquer; Charles André; Denise Madeira Moreira; Ivan Hideyo Okamoto; José Luiz de Sá Cavalcanti Journal: Dement Neuropsychol Date: 2011 Oct-Dec
Authors: Márcia L F Chaves; Claudia C Godinho; Claudia S Porto; Leticia Mansur; Maria Teresa Carthery-Goulart; Mônica S Yassuda; Rogério Beato Journal: Dement Neuropsychol Date: 2011 Jul-Sep