Literature DB >> 20464003

Biosynthesis of polyketides by trans-AT polyketide synthases.

Jörn Piel1.   

Abstract

This review discusses the biosynthesis of natural products that are generated by trans-AT polyketide synthases, a family of catalytically versatile enzymes that have recently been recognized as one of the major group of proteins involved in the production of bioactive polyketides. 436 references are cited.

Entities:  

Mesh：

Substances：

Year:  2010        PMID： 20464003     DOI： 10.1039/b816430b

Source DB:  PubMed          Journal:  Nat Prod Rep        ISSN： 0265-0568            Impact factor:   13.423


  109 in total

Review 1.  Bryostatins: biological context and biotechnological prospects.

Authors:  Amaro E Trindade-Silva; Grace E Lim-Fong; Koty H Sharp; Margo G Haygood
Journal:  Curr Opin Biotechnol       Date:  2010-12       Impact factor: 9.740

2.  Structural and evolutionary relationships of "AT-less" type I polyketide synthase ketosynthases.

Authors:  Jeremy R Lohman; Ming Ma; Jerzy Osipiuk; Boguslaw Nocek; Youngchang Kim; Changsoo Chang; Marianne Cuff; Jamey Mack; Lance Bigelow; Hui Li; Michael Endres; Gyorgy Babnigg; Andrzej Joachimiak; George N Phillips; Ben Shen
Journal:  Proc Natl Acad Sci U S A       Date:  2015-09-29       Impact factor: 11.205

Review 3.  The structural biology of biosynthetic megaenzymes.

Authors:  Kira J Weissman
Journal:  Nat Chem Biol       Date:  2015-09       Impact factor: 15.040

4.  Structure-based analysis of the molecular interactions between acyltransferase and acyl carrier protein in vicenistatin biosynthesis.

Authors:  Akimasa Miyanaga; Shohei Iwasawa; Yuji Shinohara; Fumitaka Kudo; Tadashi Eguchi
Journal:  Proc Natl Acad Sci U S A       Date:  2016-02-01       Impact factor: 11.205

Review 5.  Engineering the acyltransferase substrate specificity of assembly line polyketide synthases.

Authors:  Briana J Dunn; Chaitan Khosla
Journal:  J R Soc Interface       Date:  2013-05-29       Impact factor: 4.118

6.  Metagenomic natural product discovery in lichen provides evidence for a family of biosynthetic pathways in diverse symbioses.

Authors:  Annette Kampa; Andrey N Gagunashvili; Tobias A M Gulder; Brandon I Morinaka; Cristina Daolio; Markus Godejohann; Vivian P W Miao; Jörn Piel; Ólafur S Andrésson
Journal:  Proc Natl Acad Sci U S A       Date:  2013-07-29       Impact factor: 11.205

7.  Natural products: untwisting the antibiotic'ome.

Authors:  Chad W Johnston; Nathan A Magarvey
Journal:  Nat Chem Biol       Date:  2015-03       Impact factor: 15.040

8.  Vinylogous chain branching catalysed by a dedicated polyketide synthase module.

Authors:  Tom Bretschneider; Joel B Heim; Daniel Heine; Robert Winkler; Benjamin Busch; Björn Kusebauch; Thilo Stehle; Georg Zocher; Christian Hertweck
Journal:  Nature       Date:  2013-09-18       Impact factor: 49.962

9.  Spliceostatin hemiketal biosynthesis in Burkholderia spp. is catalyzed by an iron/α-ketoglutarate-dependent dioxygenase.

Authors:  Alessandra S Eustáquio; Jeffrey E Janso; Anokha S Ratnayake; Christopher J O'Donnell; Frank E Koehn
Journal:  Proc Natl Acad Sci U S A       Date:  2014-08-05       Impact factor: 11.205

10.  Reinvigorating natural product combinatorial biosynthesis with synthetic biology.

Authors:  Eunji Kim; Bradley S Moore; Yeo Joon Yoon
Journal:  Nat Chem Biol       Date:  2015-09       Impact factor: 15.040
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.