Literature DB >> 20455046

[Allopurinol-induced hypersensitivity syndrome resulting in death].

Sören Laurisch1, Maren Jaedtke, Reyhan Demir, Sajoscha A Sorrentino, Jan T Kielstein, Hans-Oliver Rennekampff, Peter M Vogt, Gerd P Meyer, Martin Fuchs, Gunnar Klein, Hartmut Drexler, Bernhard Schieffer, L Christian Napp.   

Abstract

The present report describes the case of a 67-year-old patient who developed an allopurinol-induced hypersensitivity syndrome (AHS) with toxic epidermal necrolysis and subsequently died of septic multiorgan failure. Considering the increasing prescription rate of allopurinol, the present case report intends to demonstrate the underestimated threat of AHS.

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Year:  2010        PMID: 20455046     DOI: 10.1007/s00063-010-1037-3

Source DB:  PubMed          Journal:  Med Klin (Munich)        ISSN: 0723-5003


  19 in total

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Authors:  Robert L Wortmann
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7.  Febuxostat compared with allopurinol in patients with hyperuricemia and gout.

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8.  Correction of allopurinol dosing should be based on clearance of creatinine, but not plasma creatinine levels: another insight to allopurinol-related toxicity.

Authors:  Fernando Perez-Ruiz; Iñaki Hernando; Irama Villar; Joan M Nolla
Journal:  J Clin Rheumatol       Date:  2005-06       Impact factor: 3.517

Review 9.  Human herpesvirus 6 and drug allergy.

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10.  Allopurinol is the most common cause of Stevens-Johnson syndrome and toxic epidermal necrolysis in Europe and Israel.

Authors:  Sima Halevy; Pierre-Dominique Ghislain; Maja Mockenhaupt; Jean-Paul Fagot; Jan Nico Bouwes Bavinck; Alexis Sidoroff; Luigi Naldi; Ariane Dunant; Cecile Viboud; Jean-Claude Roujeau
Journal:  J Am Acad Dermatol       Date:  2007-10-24       Impact factor: 11.527

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  3 in total

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2.  Acute compartment syndrome of the forearm as a rare complication of toxic epidermal necrolysis: a case report.

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  3 in total

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