Literature DB >> 20454970

Treatment of head and neck cancer in the elderly: European Consensus (panel 6) at the EUFOS Congress in Vienna 2007.

Reidar Grénman1, Dominique Chevalier, Vincent Gregoire, Eugene Myers, Simon Rogers.   

Abstract

The population in developed countries is growing older, with the number of people over 85 years of age increasing especially rapidly. The incidence of a head and neck cancer increases with age, only a few patients are under 40 years of age and the highest incidence in many sites occurs in patients over 70 years of age. The aging population has increasing amounts of comorbidities. The treatment protocols for head and neck cancer have over the last two decades become intensified as a consequence of larger surgical resections with reconstruction, high dose radiotherapy often in combination with chemotherapy or targeted therapeutic drugs. Should the elderly and old patients be treated similarly to the younger counterparts or should the treatment be altered based on chronologic age? During the EUFOS Congress in Oto-Rhino-Laryngology Head and Neck Surgery in Vienna, Austria 2007, a panel addressed this issue and this is a summary of the conclusions.

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Year:  2010        PMID: 20454970     DOI: 10.1007/s00405-010-1263-6

Source DB:  PubMed          Journal:  Eur Arch Otorhinolaryngol        ISSN: 0937-4477            Impact factor:   2.503


  25 in total

Review 1.  Aging and cancer.

Authors:  B J Kennedy
Journal:  J Clin Oncol       Date:  1988-12       Impact factor: 44.544

2.  Surgical outcomes in head and neck cancer patients 80 years of age and older.

Authors:  G L Clayman; S A Eicher; M W Sicard; E Razmpa; H Goepfert
Journal:  Head Neck       Date:  1998-05       Impact factor: 3.147

Review 3.  Tolerance to chemotherapy in elderly patients with cancer.

Authors:  Ulrich Wedding; Friedemann Honecker; Carsten Bokemeyer; Ludger Pientka; Klaus Höffken
Journal:  Cancer Control       Date:  2007-01       Impact factor: 3.302

Review 4.  Treatment considerations for head and neck cancer in the elderly.

Authors:  Eric M Genden; Alessandra Rinaldo; Ashok R Shaha; Gary L Clayman; Jochen A Werner; Carlos Suárez; Alfio Ferlito
Journal:  J Laryngol Otol       Date:  2005-03       Impact factor: 1.469

5.  Randomized clinical trial on 7-day-continuous accelerated irradiation (CAIR) of head and neck cancer - report on 3-year tumour control and normal tissue toxicity.

Authors:  K Skladowski; B Maciejewski; M Golen; B Pilecki; W Przeorek; R Tarnawski
Journal:  Radiother Oncol       Date:  2000-05       Impact factor: 6.280

6.  A Radiation Therapy Oncology Group (RTOG) phase III randomized study to compare hyperfractionation and two variants of accelerated fractionation to standard fractionation radiotherapy for head and neck squamous cell carcinomas: first report of RTOG 9003.

Authors:  K K Fu; T F Pajak; A Trotti; C U Jones; S A Spencer; T L Phillips; A S Garden; J A Ridge; J S Cooper; K K Ang
Journal:  Int J Radiat Oncol Biol Phys       Date:  2000-08-01       Impact factor: 7.038

7.  Factors affecting outcome in free-tissue transfer in the elderly.

Authors:  J M Serletti; J P Higgins; S Moran; G S Orlando
Journal:  Plast Reconstr Surg       Date:  2000-07       Impact factor: 4.730

8.  The effect of age on survival and quality of life in elderly head and neck cancer patients: a long-term prospective study.

Authors:  Marc P van der Schroeff; Wynia Derks; Gerrit Jan Hordijk; Rob J de Leeuw
Journal:  Eur Arch Otorhinolaryngol       Date:  2006-11-11       Impact factor: 2.503

9.  Patients' perceived health status following primary surgery for oral and oropharyngeal cancer.

Authors:  S N Rogers; R D Miller; K Ali; A B Minhas; H F Williams; D Lowe
Journal:  Int J Oral Maxillofac Surg       Date:  2006-09-27       Impact factor: 2.789

10.  Microvascular free tissue transfer in elderly patients: the Toronto experience.

Authors:  Eamon S Beausang; Erik E Ang; Joan E Lipa; Jonathan C Irish; Dale H Brown; Patrick J Gullane; Peter C Neligan
Journal:  Head Neck       Date:  2003-07       Impact factor: 3.147

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  11 in total

1.  Cetuximab and radiation for primary and recurrent squamous cell carcinoma of the head and neck (SCCHN) in the elderly and multi-morbid patient: a single-centre experience.

Authors:  Alexandra D Jensen; Zazie P Bergmann; Helena Garcia-Huttenlocher; Kolja Freier; Jürgen Debus; Marc W Münter
Journal:  Head Neck Oncol       Date:  2010-11-26

2.  Impact of comprehensive geriatric assessment on survival, function, and nutritional status in elderly patients with head and neck cancer: protocol for a multicentre randomised controlled trial (EGeSOR).

Authors:  Lydia Brugel; Marie Laurent; Philippe Caillet; Anne Radenne; Isabelle Durand-Zaleski; Michel Martin; Melany Baron; Héloïse de Kermadec; Sylvie Bastuji-Garin; Florence Canouï-Poitrine; Elena Paillaud
Journal:  BMC Cancer       Date:  2014-06-13       Impact factor: 4.430

3.  Mortality in tongue cancer patients treated by curative surgery: a retrospective cohort study from CGRD.

Authors:  Ming-Shao Tsai; Chia-Hsuan Lai; Chuan-Pin Lee; Yao-Hsu Yang; Pau-Chung Chen; Chung-Jan Kang; Geng-He Chang; Yao-Te Tsai; Chang-Hsien Lu; Chih-Yen Chien; Chi-Kuang Young; Ku-Hao Fang; Chin-Jui Liu; Re-Ming A Yeh; Wen-Cheng Chen
Journal:  PeerJ       Date:  2016-12-15       Impact factor: 2.984

Review 4.  Treatment of Elderly Patients with Squamous Cell Carcinoma of the Head and Neck.

Authors:  Petr Szturz; Jan B Vermorken
Journal:  Front Oncol       Date:  2016-08-31       Impact factor: 6.244

5.  The Value of Laboratory Parameters for Anemia, Renal Function, Systemic Inflammation and Nutritional Status as Predictors for Outcome in Elderly Patients with Head-and-Neck Cancers.

Authors:  Alexander Rühle; Erik Haehl; Hélène David; Tobias Kalckreuth; Tanja Sprave; Raluca Stoian; Constantinos Zamboglou; Eleni Gkika; Andreas Knopf; Anca-Ligia Grosu; Nils Henrik Nicolay
Journal:  Cancers (Basel)       Date:  2020-06-26       Impact factor: 6.639

Review 6.  Head and Neck Squamous Cell Carcinoma in Elderly Patients: Role of Radiotherapy and Chemotherapy.

Authors:  Morena Fasano; Ida D'Onofrio; Maria Paola Belfiore; Antonio Angrisani; Valentina Caliendo; Carminia Maria Della Corte; Mario Pirozzi; Sergio Facchini; Marianna Caterino; Cesare Guida; Valerio Nardone; Alfonso Reginelli; Salvatore Cappabianca
Journal:  Cancers (Basel)       Date:  2022-01-18       Impact factor: 6.639

7.  The value of primary and adjuvant radiotherapy for cutaneous squamous cell carcinomas of the head-and-neck region in the elderly.

Authors:  Erik Haehl; Alexander Rühle; Rabea Klink; Tobias Kalckreuth; Tanja Sprave; Eleni Gkika; Constantinos Zamboglou; Frank Meiß; Anca-Ligia Grosu; Nils H Nicolay
Journal:  Radiat Oncol       Date:  2021-06-12       Impact factor: 3.481

8.  Radiotherapy for geriatric head-and-neck cancer patients: what is the value of standard treatment in the elderly?

Authors:  Erik Haehl; Alexander Rühle; Hélène David; Tobias Kalckreuth; Tanja Sprave; Raluca Stoian; Christoph Becker; Andreas Knopf; Anca-Ligia Grosu; Nils H Nicolay
Journal:  Radiat Oncol       Date:  2020-02-04       Impact factor: 3.481

9.  Patterns-of-Care Analysis for Radiotherapy of Elderly Head-and-Neck Cancer Patients: A Trinational Survey in Germany, Austria and Switzerland.

Authors:  Erik Haehl; Alexander Rühle; Simon Spohn; Tanja Sprave; Eleni Gkika; Constantinos Zamboglou; Anca-Ligia Grosu; Nils H Nicolay
Journal:  Front Oncol       Date:  2022-01-03       Impact factor: 6.244

10.  Chemoradiotherapy as Definitive Treatment for Elderly Patients with Head and Neck Cancer.

Authors:  Jens Müller von der Grün; Daniel Martin; Timo Stöver; Shahram Ghanaati; Claus Rödel; Panagiotis Balermpas
Journal:  Biomed Res Int       Date:  2018-01-17       Impact factor: 3.411

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