Literature DB >> 20449253

Platinum(II) compounds bearing bone-targeting group: synthesis, crystal structure and antitumor activity.

Zuqin Xue1, Miaoxin Lin, Jianhui Zhu, Junfeng Zhang, Yizhi Li, Zijian Guo.   

Abstract

Platinum(II) complexes bearing geminal bisphosphonate moieties have excellent solubility in both organic and aqueous solutions and show considerable cytotoxicity against human osteosarcoma (MG-63) and ovarian cancer (COC1) cell lines with different apoptotic pathways from that of cisplatin.

Entities:  

Mesh：

Substances：

Year:  2010        PMID： 20449253     DOI： 10.1039/b922222g

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  5 in total

Review 1.  The Next Generation of Platinum Drugs: Targeted Pt(II) Agents, Nanoparticle Delivery, and Pt(IV) Prodrugs.

Authors:  Timothy C Johnstone; Kogularamanan Suntharalingam; Stephen J Lippard
Journal:  Chem Rev       Date:  2016-02-11       Impact factor: 60.622

Review 2.  The Platin-X series: activation, targeting, and delivery.

Authors:  Uttara Basu; Bhabatosh Banik; Ru Wen; Rakesh K Pathak; Shanta Dhar
Journal:  Dalton Trans       Date:  2016-08-16       Impact factor: 4.390

3.  Synthesis and biological evaluation of novel platinum complexes of imidazolyl-containing bisphosphonates as potential anticancer agents.

Authors:  Ling Qiu; Gaochao Lv; Yang Cao; Liping Chen; Hui Yang; Shineng Luo; Meifen Zou; Jianguo Lin
Journal:  J Biol Inorg Chem       Date:  2015-11-03       Impact factor: 3.358

4.  Poly[tri-μ-aqua-di-aqua-μ-phosphono-formato-cobalt(II)sodium].

Authors:  Xu-Jian Luo; Xiu-Qing Zhang
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2013-05-18

5.  Preparation and Biological Evaluation of Two Novel Platinum(II) Complexes Based on the Ligands of Dipicolyamine Bisphosphonate Esters.

Authors:  Ling Qiu; Hong Liu; Ke Li; Gaochao Lv; Hui Yang; Xiaofeng Qin; Jianguo Lin
Journal:  Molecules       Date:  2016-02-24       Impact factor: 4.411
  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.