Literature DB >> 20445466

Hormone therapy discontinuation: physician practices after the Women's Health Initiative.

Katherine M Newton1, Susan D Reed, Louis C Grothaus, Andrea Z La Croix, Larissa Nekhlyudov, Kelly Ehrlich, Evette J Ludman.   

Abstract

OBJECTIVE: No guidelines or randomized trials address best practices for hormone therapy (HT) discontinuation.
METHODS: We conducted a survey study to explore HT discontinuation practices at Group Health and Harvard Vanguard, large integrated health systems in the Northwest and Northeast United States, focusing on differences between specialties and study site.
RESULTS: The response rate to the written questionnaire (mailed between December 2005 and May 2006) was 78.5% (736/928); this article reports the results for 483 eligible physicians. To discontinue oral HT, most physicians (91%) advised tapering, not immediate cessation (8%), and most (60%) suggested decreasing both dose and days per week. Almost 60% of physicians reported no experience with tapering patches. Harvard Vanguard physicians were more likely than Group Health physicians to encourage discontinuing HT and less likely to recommend resuming HT when a woman's symptoms returned after discontinuing HT. Physicians were most strongly influenced by their own experience (48%), advice from colleagues (25%), and the woman's preference (19%) when choosing a discontinuation strategy; only 2% relied on research evidence. Physicians endorsed various approaches to manage symptoms after HT discontinuation, most often behavioral changes (44%) and increased exercise (37%), and these approaches were more often endorsed by Harvard Vanguard physicians and obstetrician/gynecologists than Group Health physicians or family practitioners or internists.
CONCLUSIONS: Two health plans in the Northwestern and Northeastern United States have no standard protocol for HT discontinuation. Physicians customized approaches, influenced by their location, colleagues, and specialty. Research is needed to guide approaches to HT discontinuation.

Entities:  

Mesh:

Year:  2010        PMID: 20445466      PMCID: PMC2901404          DOI: 10.1097/gme.0b013e3181d2ce57

Source DB:  PubMed          Journal:  Menopause        ISSN: 1072-3714            Impact factor:   2.953


  28 in total

1.  Use of hormone replacement therapy by postmenopausal women in the United States.

Authors:  N L Keating; P D Cleary; A S Rossi; A M Zaslavsky; J Z Ayanian
Journal:  Ann Intern Med       Date:  1999-04-06       Impact factor: 25.391

2.  Women's responses to a mailed hormone replacement therapy workbook.

Authors:  K M Newton; A Z LaCroix; D S Buist; K M Delaney; L A Anderson
Journal:  Menopause       Date:  2001 Sep-Oct       Impact factor: 2.953

3.  What factors account for hormone replacement therapy prescribing frequency?

Authors:  K M Newton; A Z LaCroix; D S Buist; L A Anderson; K Delaney
Journal:  Maturitas       Date:  2001-07-25       Impact factor: 4.342

4.  Hormone therapy prescribing patterns in the United States.

Authors:  Diana S M Buist; Katherine M Newton; Diana L Miglioretti; Kevin Beverly; Maureen T Connelly; Susan Andrade; Cynthia L Hartsfield; Feifei Wei; K Arnold Chan; Larry Kessler
Journal:  Obstet Gynecol       Date:  2004-11       Impact factor: 7.661

5.  Effect of the Women's Health Initiative on women's decisions to discontinue postmenopausal hormone therapy.

Authors:  Bruce Ettinger; Deborah Grady; Anna N A Tosteson; Alice Pressman; Judith L Macer
Journal:  Obstet Gynecol       Date:  2003-12       Impact factor: 7.661

6.  Predictors of difficulty when discontinuing postmenopausal hormone therapy.

Authors:  Deborah Grady; Bruce Ettinger; Anna N A Tosteson; Alice Pressman; Judith L Macer
Journal:  Obstet Gynecol       Date:  2003-12       Impact factor: 7.661

7.  Use of alternative therapies for menopause symptoms: results of a population-based survey.

Authors:  Katherine M Newton; Diana S M Buist; Nora L Keenan; Lynda A Anderson; Andrea Z LaCroix
Journal:  Obstet Gynecol       Date:  2002-07       Impact factor: 7.661

8.  Changes in the use of postmenopausal hormone therapy after the publication of clinical trial results.

Authors:  Jennifer S Haas; Celia P Kaplan; Eric P Gerstenberger; Karla Kerlikowske
Journal:  Ann Intern Med       Date:  2004-02-03       Impact factor: 25.391

9.  Hormone therapy prescription among physicians in France and Quebec.

Authors:  Virginie Ringa; France Légaré; Sylvie Dodin; Joanna Norton; Gaston Godin; Gérard Bréart
Journal:  Menopause       Date:  2004 Jan-Feb       Impact factor: 2.953

10.  Gynecologists' trends and attitudes toward prescribing hormone replacement therapy during menopause.

Authors:  Boris Kaplan; Sarit Aschkenazi-Steinberg; Yariv Yogev; Ravit Nahum; Jaqueline Sulkes; Menahem Phisher
Journal:  Menopause       Date:  2002 Sep-Oct       Impact factor: 2.953

View more
  2 in total

1.  Awareness and experience of menopausal symptom and hormone therapy in korean postmenopausal women.

Authors:  Hee Dong Chae; Sun Young Choi; Eun Ji Cho; Yoo Mi Cho; Sa Ra Lee; Eun Sil Lee; Hyoung Moo Park
Journal:  J Menopausal Med       Date:  2014-04-28

2.  Sources of information influencing the state-of-the-science gap in hormone replacement therapy usage.

Authors:  Fiona Chew; Xianwei Wu
Journal:  PLoS One       Date:  2017-02-03       Impact factor: 3.240

  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.