Literature DB >> 20436831

Epidermoid cancers of the anal canal: current treatment.

Jennifer Blumetti1, Amir L Bastawrous.   

Abstract

Epidermoid carcinoma of the anal canal is an uncommon disease, but has increased in incidence with the HIV epidemic. Prior to the 1970s, treatment consisted of radical surgery with abdominoperineal resection. With the pioneering work of Dr. Norman Nigro, this has shifted to a nonsurgical approach, with primary treatment consisting of multimodality therapy with radiation and chemotherapy. This review provides an overview of the historical, current, and future treatments of epidermoid anal canal malignancies.

Entities:  

Keywords:  Anal canal malignancy; Nigro protocol; chemoradiation; epidermoid carcinoma

Year:  2009        PMID： 20436831      PMCID： PMC2780240          DOI： 10.1055/s-0029-1223838

Source DB:  PubMed          Journal:  Clin Colon Rectal Surg        ISSN： 1530-9681


  35 in total

1.  Practice parameters for anal squamous neoplasms.

Authors:  Phillip R Fleshner; Sridhar Chalasani; George J Chang; David H Levien; Neil H Hyman; W Donald Buie
Journal:  Dis Colon Rectum       Date:  2007-11-21       Impact factor: 4.585

2.  Anal cancer: the end of the road for neoadjuvant chemoradiotherapy?

Authors:  Rob Glynne-Jones; Suzy Mawdsley
Journal:  J Clin Oncol       Date:  2008-06-02       Impact factor: 44.544

3.  Epidermoid anal cancer: results from the UKCCCR randomised trial of radiotherapy alone versus radiotherapy, 5-fluorouracil, and mitomycin. UKCCCR Anal Cancer Trial Working Party. UK Co-ordinating Committee on Cancer Research.

Authors: 
Journal:  Lancet       Date:  1996-10-19       Impact factor: 79.321

4.  Concomitant radiotherapy and chemotherapy is superior to radiotherapy alone in the treatment of locally advanced anal cancer: results of a phase III randomized trial of the European Organization for Research and Treatment of Cancer Radiotherapy and Gastrointestinal Cooperative Groups.

Authors:  H Bartelink; F Roelofsen; F Eschwege; P Rougier; J F Bosset; D G Gonzalez; D Peiffert; M van Glabbeke; M Pierart
Journal:  J Clin Oncol       Date:  1997-05       Impact factor: 44.544

5.  The evolving treatment of anal cancer: How are we doing?

Authors:  M H Whiteford; K R Stevens; S Oh; K E Deveney
Journal:  Arch Surg       Date:  2001-08

6.  EXTRA--a multicenter phase II study of chemoradiation using a 5 day per week oral regimen of capecitabine and intravenous mitomycin C in anal cancer.

Authors:  Rob Glynne-Jones; Helen Meadows; Susan Wan; Simon Gollins; Martin Leslie; Ed Levine; Alec C McDonald; Sun Myint; Les Samuel; David Sebag-Montefiore
Journal:  Int J Radiat Oncol Biol Phys       Date:  2008-05-09       Impact factor: 7.038

Review 7.  Carcinoma of the anal canal: a local experience and review of the literature.

Authors:  Shirley Wong; Peter Gibbs; Michael Chao; Ian Jones; Steve McLaughlin; Joe Tjandra; Ian Faragher; Michael Green
Journal:  ANZ J Surg       Date:  2004-07       Impact factor: 1.872

8.  Lymphatic mapping and sentinel lymph node biopsy in epidermoid carcinoma of the anal canal.

Authors:  S Gretschel; P Warnick; A Bembenek; S Dresel; S Koswig; A String; M Hünerbein; P M Schlag
Journal:  Eur J Surg Oncol       Date:  2008-02-21       Impact factor: 4.424

9.  Fluorouracil, mitomycin, and radiotherapy vs fluorouracil, cisplatin, and radiotherapy for carcinoma of the anal canal: a randomized controlled trial.

Authors:  Jaffer A Ajani; Kathryn A Winter; Leonard L Gunderson; John Pedersen; Al B Benson; Charles R Thomas; Robert J Mayer; Michael G Haddock; Tyvin A Rich; Christopher Willett
Journal:  JAMA       Date:  2008-04-23       Impact factor: 56.272

10.  Squamous-cell carcinoma of the anal canal: predictors of treatment outcome.

Authors:  Ramin Roohipour; Sujata Patil; Karyn A Goodman; Bruce D Minsky; W Douglas Wong; José G Guillem; Philip B Paty; Martin R Weiser; Heather B Neuman; Jinru Shia; Deborah Schrag; Larissa K F Temple
Journal:  Dis Colon Rectum       Date:  2008-01-08       Impact factor: 4.585
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  2 in total

1.  The effect of dose escalation for large squamous cell carcinomas of the anal canal.

Authors:  R N Prasad; J Elson; J Kharofa
Journal:  Clin Transl Oncol       Date:  2018-04-05       Impact factor: 3.405

Review 2.  Technical aspects of radiation therapy for anal cancer.

Authors:  Eli D Scher; Inaya Ahmed; Ning J Yue; Salma K Jabbour
Journal:  J Gastrointest Oncol       Date:  2014-06
  2 in total

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