Literature DB >> 20431185

Semen quality and aging: analysis of 9.168 samples in Cordoba. Argentina.

Rosa Isabel Molina1, Ana Carolina Martini, Andrea Tissera, José Olmedo, Daniel Senestrari, Marta Fiol de Cuneo, Rubén Daniel Ruiz.   

Abstract

OBJECTIVES: Concomitantly with the actual trend towards later fathering, more detailed studies are necessary to establish the relationship between male age and seminal features. The objective of the present paper was to evaluate the relationship of men age with semen quality and with the seminal levels of epididymal and accessory gland markers.
METHODS: The study was conducted as a retrospective study of 9168 cases obtained from the Andrology and Reproduction Laboratory in Cordoba, Argentina for 10 years (1995-2004) (men ages 20 to 77). An important number of factors such as abstinence time, toxic habits, work conditions and drugs consumption has been statistically considered. The parameters measured were: seminal volume, sperm concentration, total sperm count, sperm motility, morphology and viability. Seminal levels of alpha-glucosidase, fructose and citric acid were also evaluated.
RESULTS: We detected a significant decrease in seminal volume, sperm count, motility, viability and normal morphology, and a reduction in alpha-glucosidase and fructose levels in relation to age.
CONCLUSIONS: Since semen quality is a tool for fertility prognosis estimation, the weight of evidence indicates that men may become progressively less fertile as they get older. Couples who decide to delay childbearing should be warned about this matter.

Entities:  

Mesh:

Year:  2010        PMID: 20431185

Source DB:  PubMed          Journal:  Arch Esp Urol        ISSN: 0004-0614            Impact factor:   0.436


  19 in total

1.  Long-term effect of vasectomy on spermatogenesis in men: a morphometric study.

Authors:  Yu Xiang; Peng Luo; Yun Cao; Zheng-Wei Yang
Journal:  Asian J Androl       Date:  2013-02-25       Impact factor: 3.285

Review 2.  Ignorance but not bliss: too little is known about the determinants of semen quality.

Authors:  W C L Ford
Journal:  Asian J Androl       Date:  2013-01-14       Impact factor: 3.285

Review 3.  The Disappearing Sperms: Analysis of Reports Published Between 1980 and 2015.

Authors:  Pallav Sengupta; Sulagna Dutta; Elzbieta Krajewska-Kulak
Journal:  Am J Mens Health       Date:  2016-04-19

4.  Aging results in differential regulation of DNA repair pathways in pachytene spermatocytes in the Brown Norway rat.

Authors:  Catriona Paul; Makoto Nagano; Bernard Robaire
Journal:  Biol Reprod       Date:  2011-08-24       Impact factor: 4.285

Review 5.  Spatiotemporal trends in human semen quality.

Authors:  Jacques Auger; Florence Eustache; Cécile Chevrier; Bernard Jégou
Journal:  Nat Rev Urol       Date:  2022-08-17       Impact factor: 16.430

Review 6.  Ageing of the male germ line.

Authors:  Catriona Paul; Bernard Robaire
Journal:  Nat Rev Urol       Date:  2013-02-26       Impact factor: 14.432

7.  Semen quality and time to pregnancy: the Longitudinal Investigation of Fertility and the Environment Study.

Authors:  Germaine M Buck Louis; Rajeshwari Sundaram; Enrique F Schisterman; Anne Sweeney; Courtney D Lynch; Sungduk Kim; José M Maisog; Robert Gore-Langton; Michael L Eisenberg; Zhen Chen
Journal:  Fertil Steril       Date:  2013-11-14       Impact factor: 7.329

8.  Seminal profile of 23,504 patients over the years: 7 years of experience.

Authors:  Camila Nogueira; Ivan Henrique Yoshida; Fabia Lima Vilarino; Waldemar Pereira de Carvalho; Emerson Barch Cordts; Caio Parente Barbosa
Journal:  JBRA Assist Reprod       Date:  2018-11-01

Review 9.  Effects of increased paternal age on sperm quality, reproductive outcome and associated epigenetic risks to offspring.

Authors:  Rakesh Sharma; Ashok Agarwal; Vikram K Rohra; Mourad Assidi; Muhammad Abu-Elmagd; Rola F Turki
Journal:  Reprod Biol Endocrinol       Date:  2015-04-19       Impact factor: 5.211

10.  Do aging, drinking, and having unhealthy weight have a synergistic impact on semen quality?

Authors:  Nicolás Ramírez; Gustavo Estofán; Andrea Tissera; Rosa Molina; Eugenia Mercedes Luque; Pedro Javier Torres; Arnaldo Mangeaud; Ana Carolina Martini
Journal:  J Assist Reprod Genet       Date:  2021-07-29       Impact factor: 3.412

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