| Literature DB >> 20431010 |
Martin Spangsberg Holm1, Shunmugavel Saravanamurugan, Esben Taarning.
Abstract
Presently, very few compounds of commercial interest are directly accessible from carbohydrates by using nonfermentive approaches. We describe here a catalytic process for the direct formation of methyl lactate from common sugars. Lewis acidic zeotypes, such as Sn-Beta, catalyze the conversion of mono- and disaccharides that are dissolved in methanol to methyl lactate at 160 degrees C. With sucrose as the substrate, methyl lactate yield reaches 68%, and the heterogeneous catalyst can be easily recovered by filtration and reused multiple times after calcination without any substantial change in the product selectivity.Entities:
Year: 2010 PMID: 20431010 DOI: 10.1126/science.1183990
Source DB: PubMed Journal: Science ISSN: 0036-8075 Impact factor: 47.728