| Literature DB >> 20430708 |
Abstract
Hyperoxia-induced lung injury is characterized by an influx of inflammatory cells, increased pulmonary permeability, endothelial and epithelial cell death. This review highlights the mechanistic aspects of inflammation, vascular leak and cell death. The focus will be on agents that contribute to hyperoxia-induced lung injury in developmentally appropriate animal models, and those that have been detected in human premature neonates. Copyright 2010 Elsevier Ltd. All rights reserved.Entities:
Mesh:
Year: 2010 PMID: 20430708 PMCID: PMC2910132 DOI: 10.1016/j.siny.2010.03.009
Source DB: PubMed Journal: Semin Fetal Neonatal Med ISSN: 1744-165X Impact factor: 3.926