| Literature DB >> 24578018 |
Abstract
Exposure to hyperoxia, invasive mechanical ventilation, and systemic/local sepsis are important antecedents of postnatal inflammation in the pathogenesis of bronchopulmonary dysplasia (BPD). This review will summarize information obtained from animal (baboon, lamb/sheep, rat and mouse) models that pertain to the specific inflammatory agents and signaling molecules that predispose a premature infant to BPD.Entities:
Keywords: hyperoxia; infection; invasive ventilation; lung; newborn
Mesh:
Year: 2014 PMID: 24578018 PMCID: PMC4023567 DOI: 10.1002/bdra.23220
Source DB: PubMed Journal: Birth Defects Res A Clin Mol Teratol ISSN: 1542-0752