Literature DB >> 20430595

BDNF Val66Met polymorphism is associated with aggressive behavior in schizophrenia.

G Spalletta1, D W Morris, F Angelucci, I A Rubino, I Spoletini, P Bria, G Martinotti, A Siracusano, G Bonaviri, S Bernardini, C Caltagirone, P Bossù, G Donohoe, M Gill, A P Corvin.   

Abstract

Brain-derived neurotrophic factor (BDNF) gene variants may potentially influence behaviour. In order to test this hypothesis, we investigated the relationship between BDNF Val66Met polymorphism and aggressive behaviour in a population of schizophrenic patients. Our results showed that increased number of BDNF Met alleles was associated with increased aggressive behaviour.
Copyright © 2009 Elsevier Masson SAS. All rights reserved.

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Year:  2010        PMID： 20430595     DOI： 10.1016/j.eurpsy.2009.10.008

Source DB:  PubMed          Journal:  Eur Psychiatry        ISSN： 0924-9338            Impact factor:   5.361


  22 in total

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9.  The BDNF Val66Met polymorphism and plasma brain-derived neurotrophic factor levels in Han Chinese patients with bipolar disorder and schizophrenia.

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Review 10.  Changes in mitochondrial function are pivotal in neurodegenerative and psychiatric disorders: how important is BDNF?

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