Literature DB >> 20428418

The effect of insulin on the heart : Part 1: Effects on metabolism and function.

L J Klein1, F C Visser.   

Abstract

Positive inotropic effects of insulin were described early after the isolation of insulin from the pancreas but data on the effect of insulin on the heart are conflicting. Systemic insulin administration results in a reduction in circulating free fatty acids and an improvement in myocardial glucose uptake, which causes an efficiency improvement in the myocardial cell. There is strong evidence that insulin administration results in functional improvement in dysfunctional myocardium. (Neth Heart J 2010;18:197-201.).

Entities:  

Keywords:  Heart; Heart Failure; Insulin; Metabolism; Ventribular Function

Year:  2010        PMID: 20428418      PMCID: PMC2856868          DOI: 10.1007/bf03091761

Source DB:  PubMed          Journal:  Neth Heart J        ISSN: 1568-5888            Impact factor:   2.380


  45 in total

1.  The influence of insulin upon the mammalian heart.

Authors:  M B Visscher; E A Müller
Journal:  J Physiol       Date:  1927-03-15       Impact factor: 5.182

2.  The positive inotropic action of insulin in the canine heart.

Authors:  B R Lucchesi; M Medina; F J Kniffen
Journal:  Eur J Pharmacol       Date:  1972-04       Impact factor: 4.432

3.  ATP synthesis during low-flow ischemia: influence of increased glycolytic substrate.

Authors:  A C Cave; J S Ingwall; J Friedrich; R Liao; K W Saupe; C S Apstein; F R Eberli
Journal:  Circulation       Date:  2000-05-02       Impact factor: 29.690

4.  Effect of plasma insulin level on myocardial blood flow and its mechanism of action.

Authors:  P H McNulty; S Pfau; L I Deckelbaum
Journal:  Am J Cardiol       Date:  2000-01-15       Impact factor: 2.778

5.  Glucose-insulin-potassium infusion for myocardial protection during off-pump coronary artery surgery.

Authors:  William A Lell; Vance G Nielsen; David C McGiffin; Frank E Schmidt; James K Kirklin; Alfred W Stanley
Journal:  Ann Thorac Surg       Date:  2002-04       Impact factor: 4.330

6.  Glucose insulin potassium infusion improves systolic function in patients with chronic ischemic cardiomyopathy.

Authors:  Yves Cottin; Isabelle Lhuillier; Laurent Gilson; Marianne Zeller; Caroline Bonnet; Christine Toulouse; Pierre Louis; Luc Rochette; Claude Girard; Jean-Eric Wolf
Journal:  Eur J Heart Fail       Date:  2002-03       Impact factor: 15.534

7.  Effects of dobutamine versus insulin on cardiac performance, myocardial oxygen demand, and total body metabolism after coronary artery bypass grafting.

Authors:  M Hiesmayr; W J Haider; G Grubhofer; D Heilinger; F P Keznickl; P Mares; A M Rajek; F Coraim; M Semsroth
Journal:  J Cardiothorac Vasc Anesth       Date:  1995-12       Impact factor: 2.628

8.  Insulin infusion in conscious dogs. Effects on systemic and coronary hemodynamics, regional blood flows, and plasma catecholamines.

Authors:  C Liang; J U Doherty; R Faillace; K Maekawa; S Arnold; H Gavras; W B Hood
Journal:  J Clin Invest       Date:  1982-06       Impact factor: 14.808

9.  Sustained effect of glucose-insulin-potassium on myocardial performance during regional ischemia. Role of free fatty acid and osmolality.

Authors:  S S Ahmed; C H Lee; H A Oldewurtel; T J Regan
Journal:  J Clin Invest       Date:  1978-05       Impact factor: 14.808

10.  Glucose, insulin and potassium for heart protection during cardiac surgery.

Authors:  S Bruemmer-Smith; M S Avidan; B Harris; S Sudan; R Sherwood; J B Desai; F Sutherland; J Ponte
Journal:  Br J Anaesth       Date:  2002-04       Impact factor: 9.166

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  7 in total

1.  The effect of insulin on the heart: Part 2: Effects on function during and post myocardial ischaemia.

Authors:  L J Klein; F C Visser
Journal:  Neth Heart J       Date:  2010-05       Impact factor: 2.380

2.  Caffeine and taurine containing energy drink increases left ventricular contractility in healthy volunteers.

Authors:  Jonas M Doerner; Daniel L Kuetting; Julian A Luetkens; Claas P Naehle; Darius Dabir; Rami Homsi; Jennifer Nadal; Hans H Schild; Daniel K Thomas
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3.  Improvement of continuous subcutaneous insulin infusion on patients with type 2 diabetes mellitus by 3-dimensional speckle tracking echocardiography.

Authors:  Hong-Xia Luo; Xiao-Ling Zhou; Hong-Ju Kou; Xian-Wei Ni; Qing Wu; Chun-Peng Zou; Dao-Zhu Wu; Yong-Fang Liu
Journal:  Int J Cardiovasc Imaging       Date:  2017-09-21       Impact factor: 2.357

4.  Cardiac expression of human type 2 iodothyronine deiodinase increases glucose metabolism and protects against doxorubicin-induced cardiac dysfunction in male mice.

Authors:  Eun-Gyoung Hong; Brian W Kim; Dae Young Jung; Jong Hun Kim; Tim Yu; Wagner Seixas Da Silva; Randall H Friedline; Suzy D Bianco; Stephen P Seslar; Hiroko Wakimoto; Charles I Berul; Kerry S Russell; Ki Won Lee; P Reed Larsen; Antonio C Bianco; Jason K Kim
Journal:  Endocrinology       Date:  2013-07-16       Impact factor: 4.736

5.  The blood pressure-elevating effect of Red Bull energy drink is mimicked by caffeine but through different hemodynamic pathways.

Authors:  Jennifer L Miles-Chan; Nathalie Charrière; Erik K Grasser; Jean-Pierre Montani; Abdul G Dulloo
Journal:  Physiol Rep       Date:  2015-02-25

6.  Effect of the long-acting insulin analogues glargine and degludec on cardiomyocyte cell signalling and function.

Authors:  Thorsten Hartmann; Sabrina Overhagen; D Margriet Ouwens; Silja Raschke; Paulus Wohlfart; Norbert Tennagels; Nina Wronkowitz; Jürgen Eckel
Journal:  Cardiovasc Diabetol       Date:  2016-07-15       Impact factor: 9.951

7.  Overfeeding During Lactation in Rats is Associated with Cardiovascular Insulin Resistance in the Short-Term.

Authors:  Daniel González-Hedström; Lucía Guerra-Menéndez; Antonio Tejera-Muñoz; Sara Amor; María de la de la Fuente-Fernández; Beatriz Martín-Carro; Riansares Arriazu; Angel Luis Luis García-Villalón; Miriam Granado
Journal:  Nutrients       Date:  2020-02-20       Impact factor: 5.717

  7 in total

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