AIM: Colorectal cancer is one of the major cancers in the developed world. The incidence of colorectal cancer is low in India. The aim of the present study was to describe the anatomical distribution and age at diagnosis of colorectal cancer in India. METHODS: Retrospective descriptive analysis of anatomical distribution, age at diagnosis and demography of 220 cases (149 [67.7%] men) of adenocarcinoma of the colon or rectum diagnosed at colonoscopy over a period of five years. RESULTS: The mean age at diagnosis was 58.4 years (SD 13.3; range 23-85 years). Twenty-eight (12.7%) cases were below the age of 40 years. The majority (31.8%) cases were aged between 61-70 years. Most of the tumors (n=163, 74%) were located distal to the splenic flexure. Multivariate logistic regression analysis showed that bleeding per rectum (OR 2.8; 95% CI 1.2-6.2) was associated with distal cancer, and palpable mass (OR 3.9; 95% CI 1.7-8.6) was associated with proximal cancer. CONCLUSIONS: Almost one-third of the colorectal cancers in this series occurred in the seventh decade and were located distal to the splenic flexure.
AIM: Colorectal cancer is one of the major cancers in the developed world. The incidence of colorectal cancer is low in India. The aim of the present study was to describe the anatomical distribution and age at diagnosis of colorectal cancer in India. METHODS: Retrospective descriptive analysis of anatomical distribution, age at diagnosis and demography of 220 cases (149 [67.7%] men) of adenocarcinoma of the colon or rectum diagnosed at colonoscopy over a period of five years. RESULTS: The mean age at diagnosis was 58.4 years (SD 13.3; range 23-85 years). Twenty-eight (12.7%) cases were below the age of 40 years. The majority (31.8%) cases were aged between 61-70 years. Most of the tumors (n=163, 74%) were located distal to the splenic flexure. Multivariate logistic regression analysis showed that bleeding per rectum (OR 2.8; 95% CI 1.2-6.2) was associated with distal cancer, and palpable mass (OR 3.9; 95% CI 1.7-8.6) was associated with proximal cancer. CONCLUSIONS: Almost one-third of the colorectal cancers in this series occurred in the seventh decade and were located distal to the splenic flexure.
Authors: K-L Goh; K-F Quek; G T S Yeo; I N Hilmi; C-K Lee; N Hasnida; M Aznan; K-L Kwan; K-T Ong Journal: Aliment Pharmacol Ther Date: 2005-11-01 Impact factor: 8.171
Authors: Medha Sugara; Ramachandra Chowdappa; K V Veerendra Kumar; Ramesh Gawari; Shalini N Swamy; Sandeep S Kumar Journal: Indian J Surg Oncol Date: 2021-04-24
Authors: Agnelo Menino Ferreira; Shradha U Chodankar; Frederick Satiro Vaz; Delia Basil D'souza; Manojkumar S Kulkarni Journal: Indian J Community Med Date: 2021-10-13