BACKGROUND: The presence of a psychosis continuum is suggested by studies showing that schizophrenia and non-clinical psychotic symptoms in the general population share the same risk factors. However, to our knowledge no large-scale studies have been conducted which examine the specificity of these risk factors in the general population. AIM: To investigate whether socio-demographic characteristics associated with non-clinical psychotic symptoms are also associated with other psychiatric symptoms. And secondly, to examine to what extent concomitant psychiatric symptoms explain the relationship between socio-demographic characteristics and non-clinical psychotic symptoms. METHODS: In a general population sample of 4894 subjects (mean age 39 years, 45% men) from the Utrecht Health Project we investigated the associations of socio-demographical characteristics with non-clinical psychotic symptoms and other psychiatric symptoms by using the SCL-90. We examined these associations using multivariable logistic regression analyses with and without controlling for the presence of other psychiatric symptoms. RESULTS: Participants with non-clinical psychotic symptoms had an 89% probability of concomitant depressive, anxiety or phobic anxiety symptoms, compared to 11% in participants without psychotic symptoms. The risk profiles for non-clinical psychotic symptoms and other psychiatric symptoms were largely similar. Non-Dutch ethnicity was most strongly associated with non-clinical psychotic symptoms. Adjusting for other psychiatric symptoms did not increase the specificity of the risk factors. CONCLUSION: Socio-demographic risk factors for non-clinical psychotic symptoms in the general population are also risk factors for other psychiatric symptoms. The relationship between these risk factors and psychotic symptoms are for a substantial part explained by an increase in other psychiatric symptoms. (c) 2010 Elsevier B.V. All rights reserved.
BACKGROUND: The presence of a psychosis continuum is suggested by studies showing that schizophrenia and non-clinical psychotic symptoms in the general population share the same risk factors. However, to our knowledge no large-scale studies have been conducted which examine the specificity of these risk factors in the general population. AIM: To investigate whether socio-demographic characteristics associated with non-clinical psychotic symptoms are also associated with other psychiatric symptoms. And secondly, to examine to what extent concomitant psychiatric symptoms explain the relationship between socio-demographic characteristics and non-clinical psychotic symptoms. METHODS: In a general population sample of 4894 subjects (mean age 39 years, 45% men) from the Utrecht Health Project we investigated the associations of socio-demographical characteristics with non-clinical psychotic symptoms and other psychiatric symptoms by using the SCL-90. We examined these associations using multivariable logistic regression analyses with and without controlling for the presence of other psychiatric symptoms. RESULTS:Participants with non-clinical psychotic symptoms had an 89% probability of concomitant depressive, anxiety or phobic anxiety symptoms, compared to 11% in participants without psychotic symptoms. The risk profiles for non-clinical psychotic symptoms and other psychiatric symptoms were largely similar. Non-Dutch ethnicity was most strongly associated with non-clinical psychotic symptoms. Adjusting for other psychiatric symptoms did not increase the specificity of the risk factors. CONCLUSION: Socio-demographic risk factors for non-clinical psychotic symptoms in the general population are also risk factors for other psychiatric symptoms. The relationship between these risk factors and psychotic symptoms are for a substantial part explained by an increase in other psychiatric symptoms. (c) 2010 Elsevier B.V. All rights reserved.
Authors: Hwagyu Suh; Byung Dae Lee; Je Min Park; Young Min Lee; Eunsoo Moon; Hee Jeong Jeong; Soo Yeon Kim; Kang Yoon Lee; Young In Chung Journal: Psychiatry Clin Neurosci Date: 2019-02-02 Impact factor: 5.188
Authors: Richie Poulton; Mark J Van Ryzin; Gordon T Harold; Patricia Chamberlain; David Fowler; Mary Cannon; Louise Arseneault; Leslie D Leve Journal: J Am Acad Child Adolesc Psychiatry Date: 2014-09-16 Impact factor: 8.829
Authors: Johanna T W Wigman; Martine van Nierop; Wilma A M Vollebergh; Roselind Lieb; Katja Beesdo-Baum; Hans-Ullrich Wittchen; Jim van Os Journal: Schizophr Bull Date: 2012-01-18 Impact factor: 9.306
Authors: W Rössler; V Ajdacic-Gross; H Haker; S Rodgers; M Müller; M P Hengartner Journal: Epidemiol Psychiatr Sci Date: 2013-11-26 Impact factor: 6.892
Authors: Stian Solem; Kristen Hagen; Christoffer Wenaas; Åshild T Håland; Gunvor Launes; Patrick A Vogel; Bjarne Hansen; Joseph A Himle Journal: BMC Psychiatry Date: 2015-05-28 Impact factor: 3.630
Authors: Sanne H Booij; Marieke Wichers; Peter de Jonge; Sjoerd Sytema; Jim van Os; Lex Wunderink; Johanna T W Wigman Journal: BMJ Open Date: 2018-01-21 Impact factor: 2.692
Authors: D Kounali; S Zammit; N Wiles; S Sullivan; M Cannon; J Stochl; P Jones; L Mahedy; S H Gage; J Heron; G Lewis Journal: Psychol Med Date: 2014-09 Impact factor: 7.723