Literature DB >> 20420456

Polyamines in drug discovery: from the universal template approach to the multitarget-directed ligand design strategy.

Carlo Melchiorre1, Maria Laura Bolognesi, Anna Minarini, Michela Rosini, Vincenzo Tumiatti.   

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Year:  2010        PMID： 20420456     DOI： 10.1021/jm100293f

Source DB:  PubMed          Journal:  J Med Chem        ISSN： 0022-2623            Impact factor:   7.446


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  6 in total

Review 1.  Chemistry and biology of multicomponent reactions.

Authors:  Alexander Dömling; Wei Wang; Kan Wang
Journal:  Chem Rev       Date:  2012-03-22       Impact factor: 60.622

2.  Interrogating alkyl and arylalkylpolyamino (bis)urea and (bis)thiourea isosteres as potent antimalarial chemotypes against multiple lifecycle forms of Plasmodium falciparum parasites.

Authors:  Bianca K Verlinden; Marna de Beer; Boobalan Pachaiyappan; Ethan Besaans; Warren A Andayi; Janette Reader; Jandeli Niemand; Riette van Biljon; Kiplin Guy; Timothy Egan; Patrick M Woster; Lyn-Marie Birkholtz
Journal:  Bioorg Med Chem       Date:  2015-01-28       Impact factor: 3.641

3.  Synthesis of Novel G Factor or Chloroquine-Artemisinin Hybrids and Conjugates with Potent Antiplasmodial Activity.

Authors:  Dionissia A Pepe; Dimitra Toumpa; Christiane André-Barrès; Christophe Menendez; Elisabeth Mouray; Michel Baltas; Philippe Grellier; Dionissios Papaioannou; Constantinos M Athanassopoulos
Journal:  ACS Med Chem Lett       Date:  2020-03-24       Impact factor: 4.345

4.  Hydroxycinnamic acid amides from Scopolia tangutica inhibit the activity of M1 muscarinic acetylcholine receptor in vitro.

Authors:  Yan Zhang; Zhen Long; Zhimou Guo; Zhiwei Wang; Xiuli Zhang; Richard D Ye; Xinmiao Liang; Olivier Civelli
Journal:  Fitoterapia       Date:  2015-11-14       Impact factor: 2.882

Review 5.  Beyond Antioxidant Effects: Nature-Based Templates Unveil New Strategies for Neurodegenerative Diseases.

Authors:  Andrea Bacci; Massimiliano Runfola; Simona Sestito; Simona Rapposelli
Journal:  Antioxidants (Basel)       Date:  2021-02-28

6.  Novel NSAID-Derived Drugs for the Potential Treatment of Alzheimer's Disease.

Authors:  Ivana Cacciatore; Lisa Marinelli; Erika Fornasari; Laura S Cerasa; Piera Eusepi; Hasan Türkez; Cristina Pomilio; Marcella Reale; Chiara D'Angelo; Erica Costantini; Antonio Di Stefano
Journal:  Int J Mol Sci       Date:  2016-06-30       Impact factor: 5.923
  6 in total

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