STUDY OBJECTIVE: To estimate the clinical effectiveness of transcervical resection of endometrial polyps. DESIGN: Randomized controlled trial (Canadian Task Force classification I). SETTING:University teaching hospital. PATIENTS: One hundred fifty premenopausal women with endometrial polyps. INTERVENTIONS: Either transcervical resection of the polyp or observation for 6 months. MEASUREMENTS AND MAIN RESULTS: There was no difference in periodic blood loss measured using the Pictorial Blood Assessment Chart between the study groups at 6-month follow-up. A significant difference between the groups was observed in favor of the intervention group for 2 secondary outcome measures: mean difference of periodic blood loss measured using a visual analog scale (score, 0.7; 95% confidence interval, 0.11-1.30; p = .02) and occurrence of gynecologic symptoms at follow-up (7 of 75 patients [9.3%] vs 28 of 75 [37.3%]; p <.001). Data were analyzed according to the principle of intention to treat. CONCLUSION:Transcervical resection of endometrial polyps seems to have minimal effect on periodic blood loss; however, the procedure seems to relieve symptoms such as intermenstrual bleeding in most premenopausal women. Copyright 2010 AAGL. Published by Elsevier Inc. All rights reserved.
RCT Entities:
STUDY OBJECTIVE: To estimate the clinical effectiveness of transcervical resection of endometrial polyps. DESIGN: Randomized controlled trial (Canadian Task Force classification I). SETTING: University teaching hospital. PATIENTS: One hundred fifty premenopausal women with endometrial polyps. INTERVENTIONS: Either transcervical resection of the polyp or observation for 6 months. MEASUREMENTS AND MAIN RESULTS: There was no difference in periodic blood loss measured using the Pictorial Blood Assessment Chart between the study groups at 6-month follow-up. A significant difference between the groups was observed in favor of the intervention group for 2 secondary outcome measures: mean difference of periodic blood loss measured using a visual analog scale (score, 0.7; 95% confidence interval, 0.11-1.30; p = .02) and occurrence of gynecologic symptoms at follow-up (7 of 75 patients [9.3%] vs 28 of 75 [37.3%]; p <.001). Data were analyzed according to the principle of intention to treat. CONCLUSION: Transcervical resection of endometrial polyps seems to have minimal effect on periodic blood loss; however, the procedure seems to relieve symptoms such as intermenstrual bleeding in most premenopausal women. Copyright 2010 AAGL. Published by Elsevier Inc. All rights reserved.
Authors: Jan Bosteels; Steffi van Wessel; Steven Weyers; Frank J Broekmans; Thomas M D'Hooghe; M Y Bongers; Ben Willem J Mol Journal: Cochrane Database Syst Rev Date: 2018-12-05
Authors: Natalie A M Cooper; T Justin Clark; Lee Middleton; Lavanya Diwakar; Paul Smith; Elaine Denny; Tracy Roberts; Lynda Stobert; Susan Jowett; Jane Daniels Journal: BMJ Date: 2015-03-23