Literature DB >> 2041567

Two different microtubule-based motor activities with opposite polarities in kinetochores.

A A Hyman1, T J Mitchison.   

Abstract

The movement of microtubules on the kinetochores of isolated chromosomes has been examined by video microscopy. Two different microtubule-based motors on the kinetochore were identified, which have opposite directions of movement. The activities of these two motors can be regulated by factors that can influence phosphorylation.

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Year:  1991        PMID： 2041567     DOI： 10.1038/351206a0

Source DB:  PubMed          Journal:  Nature        ISSN： 0028-0836            Impact factor:   49.962


  68 in total

1.  Mechanism of the single-headed processivity: diffusional anchoring between the K-loop of kinesin and the C terminus of tubulin.

Authors:  Y Okada; N Hirokawa
Journal:  Proc Natl Acad Sci U S A       Date:  2000-01-18       Impact factor: 11.205

Review 2.  Pac-Man does not resolve the enduring problem of anaphase chromosome movement.

Authors:  J D Pickett-Heaps; A Forer
Journal:  Protoplasma       Date:  2001       Impact factor: 3.356

Review 3.  Boveri revisited.

Authors:  Anthony A Hyman
Journal:  EMBO J       Date:  2005-03-10       Impact factor: 11.598

4.  DNA topoisomerase II alpha is the major chromosome protein recognized by the mitotic phosphoprotein antibody MPM-2.

Authors:  S Taagepera; P N Rao; F H Drake; G J Gorbsky
Journal:  Proc Natl Acad Sci U S A       Date:  1993-09-15       Impact factor: 11.205

5.  The dynamic behavior of individual microtubules associated with chromosomes in vitro.

Authors:  A J Hunt; J R McIntosh
Journal:  Mol Biol Cell       Date:  1998-10       Impact factor: 4.138

6.  Disruption of CENP antigen function perturbs dynein anchoring to the mitotic kinetochore.

Authors:  L Wordeman; W C Earnshaw; R L Bernat
Journal:  Chromosoma       Date:  1996-06       Impact factor: 4.316

7.  In vitro motility from recombinant dynein heavy chain.

Authors:  M Mazumdar; A Mikami; M A Gee; R B Vallee
Journal:  Proc Natl Acad Sci U S A       Date:  1996-06-25       Impact factor: 11.205

8.  A method that allows the assembly of kinetochore components onto chromosomes condensed in clarified Xenopus egg extracts.

Authors:  A Desai; H W Deacon; C E Walczak; T J Mitchison
Journal:  Proc Natl Acad Sci U S A       Date:  1997-11-11       Impact factor: 11.205

9.  Move backward, forward signals.

Authors:  Peter Nick
Journal:  Protoplasma       Date:  2019-08-10       Impact factor: 3.356

10.  Specific association of an M-phase kinase with isolated mitotic spindles and identification of two of its substrates as MAP4 and MAP1B.

Authors:  R M Tombes; J G Peloquin; G G Borisy
Journal:  Cell Regul       Date:  1991-11
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