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Literature DB >> 20414819

Natural products and their role in cancer therapy.

Abstract

This paper documented several natural products that have antineoplastic activities. Detailed descriptions of the mechanism of action of these products are given. Side effects of these natural products are also described. Based on these side effect profiles and their benefits, these natural products could be used as adjuvant cancer therapies. Traditional anticancer agents usually have debilitating side effects. These natural products would be of great benefit due to their anticancer activities. Additionally, some of these natural products can work proactively in preventing cancer formation with their chemopreventive properties. Incorporation into diet can be recommended after discussion with physician and other health care professionals.

Entities: Disease

Mesh：

Substances：

Year: 2010 PMID： 20414819 DOI： 10.1007/s12032-010-9528-x

Source DB: PubMed Journal: Med Oncol ISSN： 1357-0560 Impact factor: 3.064

39 in total

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Journal: Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub Date: 2006-07 Impact factor: 1.245

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Journal: J Nutr Date: 2001-06 Impact factor: 4.798

5. Covalent binding of the anticancer drug ellipticine to DNA in V79 cells transfected with human cytochrome P450 enzymes.

Authors: Eva Frei; Christian A Bieler; Volker M Arlt; Manfred Wiessler; Marie Stiborová
Journal: Biochem Pharmacol Date: 2002-07-15 Impact factor: 5.858

6. Induction of apoptosis in human lung cancer cells by curcumin.

Authors: G Radhakrishna Pillai; Anand S Srivastava; Tarek I Hassanein; Dharam P Chauhan; Ewa Carrier
Journal: Cancer Lett Date: 2004-05-28 Impact factor: 8.679

7. Phyllanthus urinaria triggers the apoptosis and Bcl-2 down-regulation in Lewis lung carcinoma cells.

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Journal: Life Sci Date: 2003-02-28 Impact factor: 5.037

8. DNA adduct formation by the anticancer drug ellipticine in rats determined by 32P postlabeling.

Authors: Marie Stiborová; Andrea Breuer; Dagmar Aimová; Martina Stiborová-Rupertová; Manfred Wiessler; Eva Frei
Journal: Int J Cancer Date: 2003-12-20 Impact factor: 7.396

9. Curcumin inhibits the growth of AGS human gastric carcinoma cells in vitro and shows synergism with 5-fluorouracil.

Authors: Ja Young Koo; Hyun Joo Kim; Keun-Ok Jung; Kun-Young Park
Journal: J Med Food Date: 2004 Impact factor: 2.786

10. Inhibitory effects of ginsenoside Rh2 on tumor growth in nude mice bearing human ovarian cancer cells.

Authors: H Nakata; Y Kikuchi; T Tode; J Hirata; T Kita; K Ishii; K Kudoh; I Nagata; N Shinomiya
Journal: Jpn J Cancer Res Date: 1998-07

9 in total

1. Apoptosis of human gastric carcinoma cells induced by Euphorbia esula latex.

Authors: Zhao-Ying Fu; Xiao-Dong Han; Ai-Hong Wang; Xiao-Bin Liu
Journal: World J Gastroenterol Date: 2016-04-07 Impact factor: 5.742

2. Anti-cancerous triterpenoid saponins from Lecaniodiscus cupanioides.

Authors: S A Adesegun; H A B Coker; M T Hamann
Journal: J Nat Prod (Gorakhpur) Date: 2014

3. Anti-invasive effect of Cyclamen pseudibericum extract on A549 non-small cell lung carcinoma cells via inhibition of ZEB1 mediated by miR-200c.

Authors: Ege Riza Karagur; Cennet Ozay; Ramazan Mammadov; Hakan Akca
Journal: J Nat Med Date: 2018-03-19 Impact factor: 2.343

4. Medicarpin, a legume phytoalexin sensitizes myeloid leukemia cells to TRAIL-induced apoptosis through the induction of DR5 and activation of the ROS-JNK-CHOP pathway.

Authors: R Trivedi; R Maurya; D P Mishra
Journal: Cell Death Dis Date: 2014-10-16 Impact factor: 8.469

5. Antihepatoma activity of Artocarpus communis is higher in fractions with high artocarpin content.

Authors: Cheng-Wei Tzeng; Feng-Lin Yen; Liang-Tzung Lin; Chiang-Wen Lee; Ming-Hong Yen; Wen-Sheng Tzeng; Chun-Ching Lin
Journal: ScientificWorldJournal Date: 2014-07-14

6. Apoptosis inducing capacity of Holothuria arenicola in CT26 colon carcinoma cells in vitro and in vivo.

Authors: Javad Baharara; Elaheh Amini; Mahbubeh Afzali; Najme Nikdel; Asma Mostafapour; Mohammad Amin Kerachian
Journal: Iran J Basic Med Sci Date: 2016-04 Impact factor: 2.699

Review 7. Molecular targets of TRAIL-sensitizing agents in colorectal cancer.

Authors: Carmine Stolfi; Francesco Pallone; Giovanni Monteleone
Journal: Int J Mol Sci Date: 2012-06-25 Impact factor: 6.208

8. A Novel Cytotoxic Conjugate Derived from the Natural Product Podophyllotoxin as a Direct-Target Protein Dual Inhibitor.

Authors: Ángela-Patricia Hernández; Paula Díez; Pablo A García; Martín Pérez-Andrés; Pablo Ortega; Pablo G Jambrina; David Díez; María Ángeles Castro; Manuel Fuentes
Journal: Molecules Date: 2020-09-17 Impact factor: 4.411

Review 9. Predicting and Quantifying Antagonistic Effects of Natural Compounds Given with Chemotherapeutic Agents: Applications for High-Throughput Screening.

Authors: G Lavender Hackman; Meghan Collins; Xiyuan Lu; Alessia Lodi; John DiGiovanni; Stefano Tiziani
Journal: Cancers (Basel) Date: 2020-12-10 Impact factor: 6.575

9 in total