Literature DB >> 20412866

Clostridium difficile toxinotype XI (A-B-) exhibits unique arrangement of PaLoc and its upstream region.

Barbara Geric Stare1, Maja Rupnik.   

Abstract

Clostridium difficile toxinotype XI strains do not produce toxins A (TcdA) or B (TcdB) but do possess a nonfunctional remnant of the pathogenicity locus (PaLoc), bearing part of the sequence for tcdA. This is the first report of a type with absent upstream terminal PaLoc sequences and major genetic rearrangements of the PaLoc region. Copyright (c) 2010 Elsevier Ltd. All rights reserved.

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Year:  2010        PMID： 20412866     DOI： 10.1016/j.anaerobe.2010.04.001

Source DB:  PubMed          Journal:  Anaerobe        ISSN： 1075-9964            Impact factor:   3.331


  9 in total

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Review 2.  An Update on Clostridium difficile Toxinotyping.

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Review 3.  Clostridium difficile infection: molecular pathogenesis and novel therapeutics.

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Journal:  Expert Rev Anti Infect Ther       Date:  2014-01       Impact factor: 5.091

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Authors:  B Kullin; J Wojno; V Abratt; S J Reid
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2016-09-30       Impact factor: 3.267

6.  Prevalence and pathogenicity of binary toxin-positive Clostridium difficile strains that do not produce toxins A and B.

Authors:  C Eckert; A Emirian; A Le Monnier; L Cathala; H De Montclos; J Goret; P Berger; A Petit; A De Chevigny; H Jean-Pierre; B Nebbad; S Camiade; R Meckenstock; V Lalande; H Marchandin; F Barbut
Journal:  New Microbes New Infect       Date:  2014-11-08

7.  The complexity and diversity of the Pathogenicity Locus in Clostridium difficile clade 5.

Authors:  Briony Elliott; Kate E Dingle; Xavier Didelot; Derrick W Crook; Thomas V Riley
Journal:  Genome Biol Evol       Date:  2014-11-08       Impact factor: 3.416

8.  Characterization of Clostridioides difficile DSM 101085 with A-B-CDT+ Phenotype from a Late Recurrent Colonization.

Authors:  Thomas Riedel; Meina Neumann-Schaal; Johannes Wittmann; Isabel Schober; Julia Danielle Hofmann; Chia-Wen Lu; Antonia Dannheim; Ortrud Zimmermann; Matthias Lochner; Uwe Groß; Jörg Overmann
Journal:  Genome Biol Evol       Date:  2020-05-01       Impact factor: 3.416

9.  High Prevalence of Multidrug-Resistant Clostridioides difficile Following Extensive Use of Antimicrobials in Hospitalized Patients in Kenya.

Authors:  Winnie C Mutai; Marianne W Mureithi; Omu Anzala; Gunturu Revathi; Brian Kullin; Magdaline Burugu; Cecilia Kyany'a; Erick Odoyo; Peter Otieno; Lillian Musila
Journal:  Front Cell Infect Microbiol       Date:  2021-02-08       Impact factor: 5.293
  9 in total

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