OBJECTIVES: To assess the influence of age as an independent factor determining the prognosis and outcome of patients with acute myocardial infarction (AMI) treated using primary percutaneous coronary intervention (PCI). DESIGN: A retrospective analysis from a dedicated database. SETTING: A high-volume interventional cardiology center in the Netherlands. PARTICIPANTS: Four thousand nine hundred thirty-three consecutive patients with AMI. MEASUREMENTS: Baseline characteristics and clinical outcomes after 30 days and 1 year were compared according to age categorized in three groups: younger than 65, 65 to 74, and 75 and older. A more-detailed analysis was performed with six age groups, from younger than 40 to 80 and older. RESULTS: Of the 4,933 consecutive patients with AMI treated with PCI between 1992 and 2004, 643 were aged 75 and older. Multivariate analysis revealed that patients aged 65 to 75 had a greater risk of 1-year mortality than those younger than 65 (adjusted odds ratio (AOR)=1.57, 95% confidence interval (CI)=1.15-2.16) and that those aged 75 and older had a greater risk of 1-year mortality than those younger than 65 (AOR=3.03, 95% CI=2.14-4.29). CONCLUSION: In this retrospective analysis, older age was independently associated with greater mortality after PCI for AMI. Patients aged 65 and older had a higher risk of mortality than younger patients, and those aged 75 and older had the highest risk of mortality.
OBJECTIVES: To assess the influence of age as an independent factor determining the prognosis and outcome of patients with acute myocardial infarction (AMI) treated using primary percutaneous coronary intervention (PCI). DESIGN: A retrospective analysis from a dedicated database. SETTING: A high-volume interventional cardiology center in the Netherlands. PARTICIPANTS: Four thousand nine hundred thirty-three consecutive patients with AMI. MEASUREMENTS: Baseline characteristics and clinical outcomes after 30 days and 1 year were compared according to age categorized in three groups: younger than 65, 65 to 74, and 75 and older. A more-detailed analysis was performed with six age groups, from younger than 40 to 80 and older. RESULTS: Of the 4,933 consecutive patients with AMI treated with PCI between 1992 and 2004, 643 were aged 75 and older. Multivariate analysis revealed that patients aged 65 to 75 had a greater risk of 1-year mortality than those younger than 65 (adjusted odds ratio (AOR)=1.57, 95% confidence interval (CI)=1.15-2.16) and that those aged 75 and older had a greater risk of 1-year mortality than those younger than 65 (AOR=3.03, 95% CI=2.14-4.29). CONCLUSION: In this retrospective analysis, older age was independently associated with greater mortality after PCI for AMI. Patients aged 65 and older had a higher risk of mortality than younger patients, and those aged 75 and older had the highest risk of mortality.
Authors: Anne H van Houwelingen; Ian D Cameron; Jacobijn Gussekloo; Hein Putter; Susan Kurrle; Anton J M de Craen; Andrea B Maier; Wendy P J den Elzen; Jeanet W Blom Journal: Age (Dordr) Date: 2013-08-30
Authors: Wojciech Wańha; Damian Kawecki; Tomasz Roleder; Beata Morawiec; Sylwia Gładysz; Adam Kowalówka; Tomasz Jadczyk; Barbara Adamus; Tomasz Pawłowski; Grzegorz Smolka; Maciej Kaźmierski; Andrzej Ochała; Ewa Nowalany-Kozielska; Wojciech Wojakowski Journal: Aging Clin Exp Res Date: 2016-11-10 Impact factor: 3.636
Authors: Divan Gabriel Topal; Kiril Aleksov Ahtarovski; Jacob Lønborg; Dan Høfsten; Lars Nepper-Christensen; Kasper Kyhl; Mikkel Schoos; Adam Ali Ghotbi; Christoffer Göransson; Litten Bertelsen; Lene Holmvang; Steffen Helqvist; Frants Pedersen; Renate Schnabel; Lars Køber; Henning Kelbæk; Niels Vejlstrup; Thomas Engstrøm; Peter Clemmensen Journal: Int J Cardiol Heart Vasc Date: 2021-03-02