Literature DB >> 20406221

The application of mass-spectrometry-based protein biomarker discovery to theragnostics.

Jonathan M Street1, James W Dear.   

Abstract

Over the last decade rapid developments in mass spectrometry have allowed the identification of multiple proteins in complex biological samples. This proteomic approach has been applied to biomarker discovery in the context of clinical pharmacology (the combination of biomarker and drug now being termed 'theragnostics'). In this review we provide a roadmap for early protein biomarker discovery studies, focusing on some key questions that regularly confront researchers.

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Year:  2010        PMID： 20406221      PMCID： PMC2848410          DOI： 10.1111/j.1365-2125.2009.03610.x

Source DB:  PubMed          Journal:  Br J Clin Pharmacol        ISSN： 0306-5251            Impact factor:   4.335


  80 in total

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