Literature DB >> 20405956

Three new indole alkaloids from Trigonostemon lii.

Cheng-Jian Tan1, Ying-Tong Di, Yue-Hu Wang, Yu Zhang, Yi-Kang Si, Qiang Zhang, Suo Gao, Xu-Jia Hu, Xin Fang, Shi-Fei Li, Xiao-Jiang Hao.   

Abstract

Three unprecedented indole alkaloids, trigonoliimines A-C (1-3) with a unique polycyclic system, were isolated from the leaves of Trigonostemon lii Y. T. Chang. The structures of 1-3 were determined by the spectroscopic, computational, and CD exciton chirality approaches. Trigonoliimine A showed modest anti-HIV-1 activity (EC(50) = 0.95 microg/mL, TI = 7.9).

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Year:  2010        PMID: 20405956     DOI: 10.1021/ol100715x

Source DB:  PubMed          Journal:  Org Lett        ISSN: 1523-7052            Impact factor:   6.005


  8 in total

1.  Total synthesis, stereochemical assignment, and biological activity of all known (-)-trigonoliimines.

Authors:  Sunkyu Han; Karen C Morrison; Paul J Hergenrother; Mohammad Movassaghi
Journal:  J Org Chem       Date:  2013-10-31       Impact factor: 4.354

2.  Concise total synthesis and stereochemical revision of all (-)-trigonoliimines.

Authors:  Sunkyu Han; Mohammad Movassaghi
Journal:  J Am Chem Soc       Date:  2011-06-20       Impact factor: 15.419

Review 3.  A review on recent developments of indole-containing antiviral agents.

Authors:  Ming-Zhi Zhang; Qiong Chen; Guang-Fu Yang
Journal:  Eur J Med Chem       Date:  2014-10-23       Impact factor: 6.514

Review 4.  Plant-Based Indole Alkaloids: A Comprehensive Overview from a Pharmacological Perspective.

Authors:  Faisal Omar; Abu Montakim Tareq; Ali M Alqahtani; Kuldeep Dhama; Mohammed Abu Sayeed; Talha Bin Emran; Jesus Simal-Gandara
Journal:  Molecules       Date:  2021-04-15       Impact factor: 4.411

5.  Voacanga globosa Spirobisindole Alkaloids Exert Antiviral Activity in HIV Latently Infected Cell Lines by Targeting the NF-kB Cascade: In Vitro and In Silico Investigations.

Authors:  Ma Sheila M de Jesus; Allan Patrick G Macabeo; John Donnie A Ramos; Von Novi O de Leon; Kaori Asamitsu; Takashi Okamoto
Journal:  Molecules       Date:  2022-02-05       Impact factor: 4.411

6.  Synthesis of C2-tetrasubstituted indolin-3-ones via Cu-catalyzed oxidative dimerization of 2-aryl indoles and cross-addition with indoles.

Authors:  Anoop Singh; Satheeshvarma Vanaparthi; Sachin Choudhary; Rangan Krishnan; Indresh Kumar
Journal:  RSC Adv       Date:  2019-08-02       Impact factor: 3.361

Review 7.  An Explorer of Chemical Biology of Plant Natural Products in Southwest China, Xiaojiang Hao.

Authors:  Yue-Mao Shen; Duo-Zhi Chen
Journal:  Nat Prod Bioprospect       Date:  2018-07-21

Review 8.  Natural product sciences: an integrative approach to the innovations of plant natural products.

Authors:  Yuemao Shen; Xiaojiang Hao
Journal:  Sci China Life Sci       Date:  2020-09-14       Impact factor: 6.038

  8 in total

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