Literature DB >> 20399234

D-cycloserine in prelimbic cortex enhances relearning of an odor-reward associative task.

Irene Villarejo-Rodríguez1, Anna Vale-Martínez, Gemma Guillazo-Blanch, Margarita Martí-Nicolovius.   

Abstract

We investigated the effects of bilateral infusions in the prelimbic cortex of D-cycloserine (DCS), a partial agonist of the NMDA receptor-associated glycine site. Wistar rats underwent a training session (acquisition, three trials) and a 24-h test (two retention and two relearning trials) of a rapidly learned olfactory discrimination task. Rats infused with DCS (10 microg/site) prior to training exhibited a significant enhancement of performance in such odor-reward task, especially in relearning. (c) 2010 Elsevier B.V. All rights reserved.

Entities:  

Mesh：

Substances：

Year:  2010        PMID： 20399234     DOI： 10.1016/j.bbr.2010.04.016

Source DB:  PubMed          Journal:  Behav Brain Res        ISSN： 0166-4328            Impact factor:   3.332


  3 in total

1.  Intra-hippocampal D-cycloserine rescues decreased social memory, spatial learning reversal, and synaptophysin levels in aged rats.

Authors:  Marta Portero-Tresserra; Margarita Martí-Nicolovius; Mireia Tarrés-Gatius; Ana Candalija; Gemma Guillazo-Blanch; Anna Vale-Martínez
Journal:  Psychopharmacology (Berl)       Date:  2018-02-28       Impact factor: 4.530

2.  Effects of SSRI treatment on GABA and glutamate levels in an associative relearning paradigm.

Authors:  B Spurny; T Vanicek; R Seiger; M B Reed; M Klöbl; V Ritter; J Unterholzner; G M Godbersen; L R Silberbauer; D Pacher; S Klug; M E Konadu; G Gryglewski; S Trattnig; W Bogner; R Lanzenberger
Journal:  Neuroimage       Date:  2021-02-28       Impact factor: 7.400

3.  D-cycloserine in prelimbic cortex reverses scopolamine-induced deficits in olfactory memory in rats.

Authors:  Marta Portero-Tresserra; Paula Cristóbal-Narváez; Margarita Martí-Nicolovius; Gemma Guillazo-Blanch; Anna Vale-Martínez
Journal:  PLoS One       Date:  2013-08-02       Impact factor: 3.240
  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.