Literature DB >> 20397174

Structure-activity relationships through sequencing (StARTS) defines optimal and suboptimal RNA motif targets for small molecules.

Sai Pradeep Velagapudi1, Steven J Seedhouse, Matthew D Disney.   

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Year:  2010        PMID： 20397174      PMCID： PMC3021749          DOI： 10.1002/anie.200907257

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN： 1433-7851            Impact factor:   15.336


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  10 in total

Review 1.  Riboswitches as antibacterial drug targets.

Authors:  Kenneth F Blount; Ronald R Breaker
Journal:  Nat Biotechnol       Date:  2006-12       Impact factor: 54.908

2.  A simple ligation-based method to increase the information density in sequencing reactions used to deconvolute nucleic acid selections.

Authors:  Jessica L Childs-Disney; Matthew D Disney
Journal:  RNA       Date:  2007-12-07       Impact factor: 4.942

3.  A small molecule microarray platform to select RNA internal loop-ligand interactions.

Authors:  Jessica L Childs-Disney; Meilan Wu; Alexei Pushechnikov; Olga Aminova; Matthew D Disney
Journal:  ACS Chem Biol       Date:  2007-11-02       Impact factor: 5.100

Review 4.  MicroRNAs as therapeutic targets in human diseases.

Authors:  Kandiah Jeyaseelan; Wishva B Herath; Arunmozhiarasi Armugam
Journal:  Expert Opin Ther Targets       Date:  2007-08       Impact factor: 6.902

Review 5.  Targeting RNA with small molecules.

Authors:  Jason R Thomas; Paul J Hergenrother
Journal:  Chem Rev       Date:  2008-03-25       Impact factor: 60.622

6.  Rational and modular design of potent ligands targeting the RNA that causes myotonic dystrophy 2.

Authors:  Melissa M Lee; Alexei Pushechnikov; Matthew D Disney
Journal:  ACS Chem Biol       Date:  2009-05-15       Impact factor: 5.100

Review 7.  Myotonic dystrophy: therapeutic strategies for the future.

Authors:  Thurman M Wheeler
Journal:  Neurotherapeutics       Date:  2008-10       Impact factor: 7.620

8.  Two-dimensional combinatorial screening identifies specific aminoglycoside-RNA internal loop partners.

Authors:  Matthew D Disney; Lucas P Labuda; Dustin J Paul; Shane G Poplawski; Alexei Pushechnikov; Tuan Tran; Sai P Velagapudi; Meilan Wu; Jessica L Childs-Disney
Journal:  J Am Chem Soc       Date:  2008-07-25       Impact factor: 15.419

9.  Rational design of ligands targeting triplet repeating transcripts that cause RNA dominant disease: application to myotonic muscular dystrophy type 1 and spinocerebellar ataxia type 3.

Authors:  Alexei Pushechnikov; Melissa M Lee; Jessica L Childs-Disney; Krzysztof Sobczak; Jonathan M French; Charles A Thornton; Matthew D Disney
Journal:  J Am Chem Soc       Date:  2009-07-22       Impact factor: 15.419

10.  Two-dimensional combinatorial screening and the RNA Privileged Space Predictor program efficiently identify aminoglycoside-RNA hairpin loop interactions.

Authors:  Dustin J Paul; Steven J Seedhouse; Matthew D Disney
Journal:  Nucleic Acids Res       Date:  2009-09-02       Impact factor: 16.971
  10 in total
  32 in total

Review 1.  RNA Structural Differentiation: Opportunities with Pattern Recognition.

Authors:  Christopher S Eubanks; Amanda E Hargrove
Journal:  Biochemistry       Date:  2018-12-18       Impact factor: 3.162

Review 2.  Small molecule targeting of RNA structures in neurological disorders.

Authors:  Alicia J Angelbello; Jonathan L Chen; Matthew D Disney
Journal:  Ann N Y Acad Sci       Date:  2019-04-09       Impact factor: 5.691

3.  Targeting RNA with Small Molecules To Capture Opportunities at the Intersection of Chemistry, Biology, and Medicine.

Authors:  Matthew D Disney
Journal:  J Am Chem Soc       Date:  2019-04-19       Impact factor: 15.419

4.  Two-dimensional combinatorial screening enables the bottom-up design of a microRNA-10b inhibitor.

Authors:  Sai Pradeep Velagapudi; Matthew D Disney
Journal:  Chem Commun (Camb)       Date:  2014-03-21       Impact factor: 6.222

Review 5.  Methods to enable the design of bioactive small molecules targeting RNA.

Authors:  Matthew D Disney; Ilyas Yildirim; Jessica L Childs-Disney
Journal:  Org Biomol Chem       Date:  2014-02-21       Impact factor: 3.876

6.  Studying modification of aminoglycoside antibiotics by resistance-causing enzymes via microarray.

Authors:  Matthew D Disney
Journal:  Methods Mol Biol       Date:  2012

Review 7.  Structure based approaches for targeting non-coding RNAs with small molecules.

Authors:  Matthew D Shortridge; Gabriele Varani
Journal:  Curr Opin Struct Biol       Date:  2015-02-16       Impact factor: 6.809

8.  Defining RNA motif-aminoglycoside interactions via two-dimensional combinatorial screening and structure-activity relationships through sequencing.

Authors:  Sai Pradeep Velagapudi; Matthew D Disney
Journal:  Bioorg Med Chem       Date:  2013-05-07       Impact factor: 3.641

Review 9.  Small molecules targeting microRNA for cancer therapy: Promises and obstacles.

Authors:  Di Wen; Michael Danquah; Amit Kumar Chaudhary; Ram I Mahato
Journal:  J Control Release       Date:  2015-08-06       Impact factor: 9.776

10.  Small-molecule-mediated cleavage of RNA in living cells.

Authors:  Lirui Guan; Matthew D Disney
Journal:  Angew Chem Int Ed Engl       Date:  2012-12-20       Impact factor: 15.336
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