Literature DB >> 20388127

Themed section: Imaging in pharmacology.

Anthony P Davenport, Craig Daly.   

Abstract

This themed section on Imaging in Pharmacology comprising reviews and original articles arose from two symposia held at the Summer Meeting of the British Pharmacological Society in Edinburgh 8-10 July 2009 on Developments in Receptor Imaging and Imaging and Targeting Inflammation in Stroke and Atherosclerosis. The reports cover a broad spectrum of pharmacological studies, from whole animal imaging to gene expression and emphasize the importance of imaging techniques in pharmacology. The development of each new imaging methodology brings pharmacology closer to the ambitious goal of being able to image (simultaneously) each component part of the G-protein-coupled receptor signalling process.

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Year:  2010        PMID: 20388127      PMCID: PMC2829199          DOI: 10.1111/j.1476-5381.2010.00685.x

Source DB:  PubMed          Journal:  Br J Pharmacol        ISSN: 0007-1188            Impact factor:   8.739


  15 in total

Review 1.  Fluorescent ligands, antibodies, and proteins for the study of receptors.

Authors:  Craig J Daly; John C McGrath
Journal:  Pharmacol Ther       Date:  2003-11       Impact factor: 12.310

Review 2.  Trafficking and signalling of gonadotrophin-releasing hormone receptors: an automated imaging approach.

Authors:  A R Finch; K R Sedgley; S P Armstrong; C J Caunt; C A McArdle
Journal:  Br J Pharmacol       Date:  2009-11-03       Impact factor: 8.739

3.  Alpha1A/B-knockout mice explain the native alpha1D-adrenoceptor's role in vasoconstriction and show that its location is independent of the other alpha1-subtypes.

Authors:  L Methven; P C Simpson; J C McGrath
Journal:  Br J Pharmacol       Date:  2009-12       Impact factor: 8.739

4.  Positron emission tomography of [18F]-big endothelin-1 reveals renal excretion but tissue-specific conversion to [18F]-endothelin-1 in lung and liver.

Authors:  Peter Johnström; Tim D Fryer; Hugh K Richards; Janet J Maguire; John C Clark; John D Pickard; Anthony P Davenport
Journal:  Br J Pharmacol       Date:  2010-02       Impact factor: 8.739

5.  Advances in imaging of new targets for pharmacological intervention in stroke: real-time tracking of T-cells in the ischaemic brain.

Authors:  F Ortolano; P Maffia; G Dever; G Rodolico; O R Millington; M G De Simoni; J M Brewer; T J Bushell; P Garside; H V Carswell
Journal:  Br J Pharmacol       Date:  2009-12-10       Impact factor: 8.739

6.  The alpha 1B/D-adrenoceptor knockout mouse permits isolation of the vascular alpha 1A-adrenoceptor and elucidates its relationship to the other subtypes.

Authors:  L Methven; M McBride; G A Wallace; J C McGrath
Journal:  Br J Pharmacol       Date:  2009-06-30       Impact factor: 8.739

Review 7.  Visualization of gene expression in the live subject using the Na/I symporter as a reporter gene: applications in biotherapy.

Authors:  Patrick Baril; Pilar Martin-Duque; Georges Vassaux
Journal:  Br J Pharmacol       Date:  2009-10-08       Impact factor: 8.739

8.  Dynamic in vivo imaging of receptors in small animals using positron emission tomography.

Authors:  Peter Johnström; Tim D Fryer; Hugh K Richards; Olivier Barret; Anthony P Davenport
Journal:  Methods Mol Biol       Date:  2005

9.  Positron emission tomography using 18F-labelled endothelin-1 reveals prevention of binding to cardiac receptors owing to tissue-specific clearance by ET B receptors in vivo.

Authors:  Peter Johnström; Tim D Fryer; Hugh K Richards; Neil G Harris; Olivier Barret; John C Clark; John D Pickard; Anthony P Davenport
Journal:  Br J Pharmacol       Date:  2005-01       Impact factor: 8.739

Review 10.  Pharmacology under the microscope: the use of fluorescence correlation spectroscopy to determine the properties of ligand-receptor complexes.

Authors:  Stephen J Briddon; Stephen J Hill
Journal:  Trends Pharmacol Sci       Date:  2007-11-14       Impact factor: 14.819

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  1 in total

1.  Imaging--the interface with pharmacology: looking to the future.

Authors:  Andrew J Lawrence; Andreas Heinz
Journal:  Br J Pharmacol       Date:  2011-08       Impact factor: 8.739

  1 in total

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