Literature DB >> 20387142

Progress in siRNA delivery using multifunctional nanoparticles.

Weiwei Gao1, Zeyu Xiao, Alex Radovic-Moreno, Jinjun Shi, Robert Langer, Omid C Farokhzad.   

Abstract

Nanoparticles made from synthetic polymers have been developed to deliver small interfering RNA (siRNA). For successful siRNA delivery, these nanoparticles need to efficiently encapsulate siRNA, actively target sites of interest, and release siRNA intracellularly. This chapter reviews recent progress using a multifunctional approach to design and engineer polymeric nanoparticles for siRNA delivery.

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Year:  2010        PMID： 20387142     DOI： 10.1007/978-1-60761-657-3_4

Source DB:  PubMed          Journal:  Methods Mol Biol        ISSN： 1064-3745


  12 in total

1.  Nanoparticle-mediated delivery of shRNA.VEGF-a plasmids regresses corneal neovascularization.

Authors:  Yureeda Qazi; Brian Stagg; Nirbhai Singh; Swita Singh; Xiaohui Zhang; Ling Luo; Jacquelyn Simonis; Uday B Kompella; Balamurali K Ambati
Journal:  Invest Ophthalmol Vis Sci       Date:  2012-05-14       Impact factor: 4.799

2.  Image-guided breast tumor therapy using a small interfering RNA nanodrug.

Authors:  Mohanraja Kumar; Mehmet Yigit; Guangping Dai; Anna Moore; Zdravka Medarova
Journal:  Cancer Res       Date:  2010-08-11       Impact factor: 12.701

Review 3.  Protein and oligonucleotide delivery systems for vaginal microbicides against viral STIs.

Authors:  Jill M Steinbach
Journal:  Cell Mol Life Sci       Date:  2014-10-17       Impact factor: 9.261

4.  Nanomedicines for Endothelial Disorders.

Authors:  Bomy Lee Chung; Michael J Toth; Nazila Kamaly; Yoshitaka J Sei; Jacob Becraft; Willem J M Mulder; Zahi A Fayad; Omid C Farokhzad; YongTae Kim; Robert Langer
Journal:  Nano Today       Date:  2015-12-01       Impact factor: 20.722

Review 5.  Bioengineering strategies for designing targeted cancer therapies.

Authors:  Angela A Alexander-Bryant; Wendy S Vanden Berg-Foels; Xuejun Wen
Journal:  Adv Cancer Res       Date:  2013       Impact factor: 6.242

6.  Cell penetrating peptide-modified poly(lactic-co-glycolic acid) nanoparticles with enhanced cell internalization.

Authors:  Jill M Steinbach; Young-Eun Seo; W Mark Saltzman
Journal:  Acta Biomater       Date:  2015-11-18       Impact factor: 8.947

7.  Delivery of chemo-sensitizing siRNAs to HER2+-breast cancer cells using RNA aptamers.

Authors:  Kristina W Thiel; Luiza I Hernandez; Justin P Dassie; William H Thiel; Xiuying Liu; Katie R Stockdale; Alissa M Rothman; Frank J Hernandez; James O McNamara; Paloma H Giangrande
Journal:  Nucleic Acids Res       Date:  2012-03-30       Impact factor: 16.971

Review 8.  Self-Amplifying Replicon RNA Vaccine Delivery to Dendritic Cells by Synthetic Nanoparticles.

Authors:  Kenneth C McCullough; Panagiota Milona; Lisa Thomann-Harwood; Thomas Démoulins; Pavlos Englezou; Rolf Suter; Nicolas Ruggli
Journal:  Vaccines (Basel)       Date:  2014-10-16

Review 9.  Nanoparticle-mediated systemic delivery of siRNA for treatment of cancers and viral infections.

Authors:  Mohamed Shehata Draz; Binbin Amanda Fang; Pengfei Zhang; Zhi Hu; Shenda Gu; Kevin C Weng; Joe W Gray; Fanqing Frank Chen
Journal:  Theranostics       Date:  2014-06-11       Impact factor: 11.556

Review 10.  NANOMEDICINE: will it offer possibilities to overcome multiple drug resistance in cancer?

Authors:  Sten Friberg; Andreas M Nyström
Journal:  J Nanobiotechnology       Date:  2016-03-09       Impact factor: 10.435
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