Literature DB >> 20380407

Synthesis of the C9-C23 (C9'-C23') fragment of the dimeric natural product rhizopodin.

Zheng Chen1, Liankai Song, Zhengshuang Xu, Tao Ye.   

Abstract

A stereoselective assembly of the C9-C23 (C9'-C23') fragment of rhizopodin, a 38-membered bis-lactone natural product, has been developed. A highly efficient approach to this fragment assembles >50% of the carbon skeleton and the stereochemical elements present in the natural product.

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Year:  2010        PMID： 20380407     DOI： 10.1021/ol100515m

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  4 in total

1.  Total synthesis and biological evaluation of monorhizopodin and 16-epi-monorhizopodin.

Authors:  K C Nicolaou; Xuefeng Jiang; Peter J Lindsay-Scott; Andrei Corbu; Sawako Yamashiro; Andrea Bacconi; Velia M Fowler
Journal:  Angew Chem Int Ed Engl       Date:  2011-01-07       Impact factor: 15.336

Review 2.  Challenges and discoveries in the total synthesis of complex polyketide natural products.

Authors:  Ian Paterson; Nelson Yuen Sum Lam
Journal:  J Antibiot (Tokyo)       Date:  2017-10-25       Impact factor: 2.649

Review 3.  Macrocyclic drugs and synthetic methodologies toward macrocycles.

Authors:  Xufen Yu; Dianqing Sun
Journal:  Molecules       Date:  2013-05-24       Impact factor: 4.411

4.  An Effective Bifunctional Aldehyde Linchpin for Type II Anion Relay Chemistry: Development and Application to the Synthesis of a C16-C29 Fragment of Rhizopodin.

Authors:  Bruno Melillo; Ming Z Chen; Roberto Forestieri; Amos B Smith
Journal:  Org Lett       Date:  2015-12-07       Impact factor: 6.005
  4 in total

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