BACKGROUND: While the validity of self-reported consumption based on blood alcohol concentration (BAC) has been found to be high in emergency room (ER) samples, little research exists on the estimated number of drinks consumed given a BAC level. Such data would be useful in establishing a dose-response relationship between drinking and risk (e.g., of injury) in those studies for which the number of drinks consumed is not available but BAC is. METHODS: Several methods were used to estimate the number of drinks consumed in the 6 hours prior to injury based on BAC obtained at the time of ER admission of n = 1,953 patients who self-reported any drinking 6 hours prior to their injury and who arrived to the ER within 6 hours of the event, from the merged Emergency Room Collaborative Alcohol Analysis Project (ERCAAP) and the World Health Organization Collaborative Study on Alcohol and Injury across 16 countries. RESULTS: The relationship between self-reported consumption and averaged BAC within each consumption level appeared to be fairly linear up to about 7 drinks and a BAC of approximately 100 mg/dl. Above about 7 reported drinks, BAC appeared to have no relationship with drinking, possibly representing longer consumption periods than only the 6 hours before injury for those reporting higher quantities consumed. Both the volume estimate from the bivariate BAC to self-report relationship as well as from a Widmark calculation using BAC and time from last drink to arrival to the ER indicated a somewhat weak relationship to actual number of self-reported drinks. CONCLUSIONS: Future studies may benefit from investigating the factors suspected to be driving the weak relationships between these measures, including the actual time over which the reported alcohol was consumed and pattern of drinking over the consumption period.
BACKGROUND: While the validity of self-reported consumption based on blood alcohol concentration (BAC) has been found to be high in emergency room (ER) samples, little research exists on the estimated number of drinks consumed given a BAC level. Such data would be useful in establishing a dose-response relationship between drinking and risk (e.g., of injury) in those studies for which the number of drinks consumed is not available but BAC is. METHODS: Several methods were used to estimate the number of drinks consumed in the 6 hours prior to injury based on BAC obtained at the time of ER admission of n = 1,953 patients who self-reported any drinking 6 hours prior to their injury and who arrived to the ER within 6 hours of the event, from the merged Emergency Room Collaborative Alcohol Analysis Project (ERCAAP) and the World Health Organization Collaborative Study on Alcohol and Injury across 16 countries. RESULTS: The relationship between self-reported consumption and averaged BAC within each consumption level appeared to be fairly linear up to about 7 drinks and a BAC of approximately 100 mg/dl. Above about 7 reported drinks, BAC appeared to have no relationship with drinking, possibly representing longer consumption periods than only the 6 hours before injury for those reporting higher quantities consumed. Both the volume estimate from the bivariate BAC to self-report relationship as well as from a Widmark calculation using BAC and time from last drink to arrival to the ER indicated a somewhat weak relationship to actual number of self-reported drinks. CONCLUSIONS: Future studies may benefit from investigating the factors suspected to be driving the weak relationships between these measures, including the actual time over which the reported alcohol was consumed and pattern of drinking over the consumption period.
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Authors: Courtney L Kraus; Natasha C Salazar; Jamie R Mitchell; Whitney D Florin; Bob Guenther; David Brady; Scott H Swartzwelder; Aaron M White Journal: Alcohol Clin Exp Res Date: 2005-09 Impact factor: 3.455
Authors: B Taylor; H M Irving; F Kanteres; R Room; G Borges; C Cherpitel; T Greenfield; J Rehm Journal: Drug Alcohol Depend Date: 2010-03-16 Impact factor: 4.492
Authors: Sean P Farris; Brien P Riley; Robert W Williams; Megan K Mulligan; Michael F Miles; Marcelo F Lopez; Robert Hitzemann; Ovidiu D Iancu; Alexander Colville; Nicole A R Walter; Priscila Darakjian; Denesa L Oberbeck; James B Daunais; Christina L Zheng; Robert P Searles; Shannon K McWeeney; Kathleen A Grant; R Dayne Mayfield Journal: Alcohol Date: 2017-12-06 Impact factor: 2.405
Authors: Amy E Adkins; Laura M Hack; Tim B Bigdeli; Vernell S Williamson; G Omari McMichael; Mohammed Mamdani; Alexis C Edwards; Fazil Aliev; Robin F Chan; Poonam Bhandari; Richard C Raabe; Joseph T Alaimo; GinaMari G Blackwell; Arden Moscati; Ryan S Poland; Benjamin Rood; Diana G Patterson; Dermot Walsh; John B Whitfield; Gu Zhu; Grant W Montgomery; Anjali K Henders; Nicholas G Martin; Andrew C Heath; Pamela A F Madden; Josef Frank; Monika Ridinger; Norbert Wodarz; Michael Soyka; Peter Zill; Marcus Ising; Markus M Nöthen; Falk Kiefer; Marcella Rietschel; Joel Gelernter; Richard Sherva; Ryan Koesterer; Laura Almasy; Hongyu Zhao; Henry R Kranzler; Lindsay A Farrer; Brion S Maher; Carol A Prescott; Danielle M Dick; Silviu A Bacanu; Laura D Mathies; Andrew G Davies; Vladimir I Vladimirov; Mike Grotewiel; M Scott Bowers; Jill C Bettinger; Bradley T Webb; Michael F Miles; Kenneth S Kendler; Brien P Riley Journal: Alcohol Clin Exp Res Date: 2017-03-30 Impact factor: 3.455