Literature DB >> 20372018

The synergistic antibacterial activity of 1-acetyl-beta-carboline and beta-lactams against methicillin-resistant Staphylococcus aureus (MRSA).

Hee Jae Shin1, Hyi-Seung Lee, Dae-Sung Lee.   

Abstract

1-Acetyl-beta-carboline was isolated as an anti-MRSA agent from the fermentation broth of a marine actinomycete isolated from marine sediment. The producing strain was identified to be Streptomyces sp. by phylogenetic analysis of the 16S rRNA gene sequence. The anti-MRSA agent was isolated by bioactivity-guided fractionation of the culture extract by solvent partitioning, ODS open flash chromatography, and purification with a reversed-phase HPLC. Its structure was elucidated by extensive 2D NMR and mass spectral analyses. Combination of 1-acetyl-beta- carboline with ampicillin exhibited synergistic antibacterial activity against MRSA.

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Year:  2010        PMID： 20372018

Source DB:  PubMed          Journal:  J Microbiol Biotechnol        ISSN： 1017-7825            Impact factor:   2.351


  12 in total

1.  Pseudonocardia cytotoxica sp. nov., a novel actinomycete isolated from an Arctic fjord with potential to produce cytotoxic compound.

Authors:  Mohandas Dhaneesha; Md Umar; Titus Susan Merlin; Kottekkatu Padinchati Krishnan; Vrinda Sukumaran; Rupesh Kumar Sinha; Abdulaziz Anas; Peng Fu; John Bryan MacMillan; Thavarool Puthiyedathu Sajeevan
Journal:  Antonie Van Leeuwenhoek       Date:  2020-11-23       Impact factor: 2.271

2.  Bile Acid 7α-Dehydroxylating Gut Bacteria Secrete Antibiotics that Inhibit Clostridium difficile: Role of Secondary Bile Acids.

Authors:  Jason D Kang; Christopher J Myers; Spencer C Harris; Genta Kakiyama; In-Kyoung Lee; Bong-Sik Yun; Keiichi Matsuzaki; Megumi Furukawa; Hae-Ki Min; Jasmohan S Bajaj; Huiping Zhou; Phillip B Hylemon
Journal:  Cell Chem Biol       Date:  2018-10-25       Impact factor: 8.116

3.  Alkaloids from the mangrove-derived actinomycete Jishengella endophytica 161111.

Authors:  Pei Wang; Fandong Kong; Jingjing Wei; Yi Wang; Wei Wang; Kui Hong; Weiming Zhu
Journal:  Mar Drugs       Date:  2014-01-21       Impact factor: 5.118

4.  Microbial diversity of saline environments: searching for cytotoxic activities.

Authors:  Carolina Díaz-Cárdenas; Angela Cantillo; Laura Yinneth Rojas; Tito Sandoval; Susana Fiorentino; Jorge Robles; Freddy A Ramos; María Mercedes Zambrano; Sandra Baena
Journal:  AMB Express       Date:  2017-12-22       Impact factor: 3.298

5.  Antibacterial Activity of Endophytic Actinomycetes Isolated from the Medicinal Plant Vochysia divergens (Pantanal, Brazil).

Authors:  Francielly M W R Gos; Daiani C Savi; Khaled A Shaaban; Jon S Thorson; Rodrigo Aluizio; Yvelise M Possiede; Jürgen Rohr; Chirlei Glienke
Journal:  Front Microbiol       Date:  2017-09-06       Impact factor: 5.640

Review 6.  Streptomyces as a Prominent Resource of Future Anti-MRSA Drugs.

Authors:  Hefa Mangzira Kemung; Loh Teng-Hern Tan; Tahir Mehmood Khan; Kok-Gan Chan; Priyia Pusparajah; Bey-Hing Goh; Learn-Han Lee
Journal:  Front Microbiol       Date:  2018-09-24       Impact factor: 5.640

7.  Pseudomonas koreensis Recovered From Raw Yak Milk Synthesizes a β-Carboline Derivative With Antimicrobial Properties.

Authors:  Manpreet Kaur; Manoj Jangra; Harjodh Singh; Rushikesh Tambat; Nittu Singh; Sanjay M Jachak; Sunita Mishra; Charu Sharma; Hemraj Nandanwar; Anil Kumar Pinnaka
Journal:  Front Microbiol       Date:  2019-07-29       Impact factor: 5.640

8.  Bioassay-Guided Interpretation of Antimicrobial Compounds in Kumu, a TCM Preparation From Picrasma quassioides' Stem via UHPLC-Orbitrap-Ion Trap Mass Spectrometry Combined With Fragmentation and Retention Time Calculation.

Authors:  Haibo Hu; Changling Hu; Jinnian Peng; Alokesh Kumar Ghosh; Ajmal Khan; Dan Sun; Walter Luyten
Journal:  Front Pharmacol       Date:  2021-10-27       Impact factor: 5.988

9.  Growth inhibition of an Araucaria angustifolia (Coniferopsida) fungal seed pathogen, Neofusicoccum parvum, by soil streptomycetes.

Authors:  Fernando Rostirolla Dalmas; Leandro Astarita; Luigi Defilippis; Elisabeth Magel; Hans-Peter Fiedler; Robert Bauer; Rüdiger Hampp
Journal:  BMC Microbiol       Date:  2013-07-18       Impact factor: 3.605

10.  Soil Bacteria Isolated From Tunisian Arid Areas Show Promising Antimicrobial Activities Against Gram-Negatives.

Authors:  Zina Nasfi; Henrik Busch; Stefan Kehraus; Luis Linares-Otoya; Gabriele M König; Till F Schäberle; Rafik Bachoual
Journal:  Front Microbiol       Date:  2018-11-13       Impact factor: 5.640
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