| Literature DB >> 203716 |
J L Waner, J E Budnick, T B Albrecht.
Abstract
Infection of permissive cells with either rhesus or vervet cytomegalovirus resulted in suppression of cellular DNA synthesis, only viral DNA was resolved by isopycnic centrifugation after 24 h postinoculation. Infection of 5-iodo-2'-deoxyuridine (IUdR)-arrested cells with either of the simian cytomegaloviruses, however, induced synthesis of cellular DNA of normal density; synthesis of cellular DNA substituted with IUdR as evidenced by resolution of a heavy DNA peak after isopycnic centrifugation was not observed. Stimulation of DNA synthesis in IUdR-arrested cells was not observed with virus inactivated with UV light.Entities:
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Year: 1978 PMID: 203716 PMCID: PMC353957
Source DB: PubMed Journal: J Virol ISSN: 0022-538X Impact factor: 5.103