Literature DB >> 165525

Stimulation of macromolecular synethesis in guinea pig cells by human CMV.

T Furukawa, S Tanaka, S A Plotkin.   

Abstract

Nonproductive human CMV infection of G.P. embryo cells induced cellular RNA and DNA synthesis. RNA species synthesized in abortively infected G.P. cells included ribosomal 28S, 18S, and 4S transfer RNA. Virus inactivated with heat and UV light failed to induce cellular RNA and DNA synthesis. Evidence for increased DNA and RNA synthesis in infected cells was provided by studies of:(a) incorporation of thymidine and uridine, (b) extraction and separation of cellular DNA and RNA on sedimentation gradients, (c) autoradiography, and (d) measurement of mitotic index.

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Year:  1975        PMID: 165525     DOI: 10.3181/00379727-148-38508

Source DB:  PubMed          Journal:  Proc Soc Exp Biol Med        ISSN: 0037-9727


  17 in total

1.  The early effects of human cytomegalovirus infection on macromolecular synthesis in human embryonic fibroblasts. Brief report.

Authors:  H M Garnett
Journal:  Arch Virol       Date:  1979       Impact factor: 2.574

2.  Synthesis of proteins and glycoproteins in cells infected with human cytomegalovirus.

Authors:  M F Stinski
Journal:  J Virol       Date:  1977-09       Impact factor: 5.103

3.  Sequence of protein synthesis in cells infected by human cytomegalovirus: early and late virus-induced polypeptides.

Authors:  M F Stinski
Journal:  J Virol       Date:  1978-06       Impact factor: 5.103

4.  Effect of rhesus or vervet cytomegalovirus infection of DNA synthesis in untreated and 5-iodo-2'-deoxyuridine-arrested cells.

Authors:  J L Waner; J E Budnick; T B Albrecht
Journal:  J Virol       Date:  1978-02       Impact factor: 5.103

5.  Patterns of transcription of human cytomegalovirus in permissively infected cells.

Authors:  J M DeMarchi; C A Schmidt; A S Kaplan
Journal:  J Virol       Date:  1980-08       Impact factor: 5.103

6.  Temporal patterns of human cytomegalovirus transcription: mapping the viral RNAs synthesized at immediate early, early, and late times after infection.

Authors:  M W Wathen; M F Stinski
Journal:  J Virol       Date:  1982-02       Impact factor: 5.103

7.  Demonstration of immunoglobulin G receptors induced by human cytomegalovirus.

Authors:  T Furukawa; E Hornberger; S Sakuma; S A Plotkin
Journal:  J Clin Microbiol       Date:  1975-10       Impact factor: 5.948

8.  Replication of human cytomegalovirus DNA: lack of dependence on cell DNA synthesis.

Authors:  J M DeMarchi; A S Kaplan
Journal:  J Virol       Date:  1976-06       Impact factor: 5.103

9.  Cytomegalovirus infection induces high levels of cyclins, phosphorylated Rb, and p53, leading to cell cycle arrest.

Authors:  F M Jault; J M Jault; F Ruchti; E A Fortunato; C Clark; J Corbeil; D D Richman; D H Spector
Journal:  J Virol       Date:  1995-11       Impact factor: 5.103

10.  Enhancement of deoxyguanosine kinase activity in human lung fibroblast cells infected with human cytomegalovirus.

Authors:  R A Lewis; L Watkins; S St Jeor
Journal:  Mol Cell Biochem       Date:  1984-11       Impact factor: 3.396

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