Literature DB >> 20370754

Potentially inappropriate medication utilization in the emergency department visits by older adults: analysis from a nationally representative sample.

William J Meurer1, Tommy A Potti, Kevin A Kerber, Comilla Sasson, Michelle L Macy, Brady T West, Eve D Losman.   

Abstract

OBJECTIVES: The objectives were to determine the frequency of administration of potentially inappropriate medications (PIMs) to older emergency department (ED) patients and to examine recent trends in the rates of PIM usage.
METHODS: The data examined during the study were obtained from the National Hospital Ambulatory Medical Care Survey (NHAMCS). This study utilized the nationally representative ED data from 2000-2006 NHAMCS surveys. Our sample included older adults (age 65 years and greater) who were treated in the ED and discharged home. Estimated frequencies of PIM-associated ED visits were calculated. A multivariable logistic regression model was created to assess demographic, clinical, and hospital factors associated with PIM administration and to assess temporal trends.
RESULTS: Approximately 19.5 million patients, or 16.8% (95% confidence interval [CI]=16.1% to 17.4%) of eligible ED visits, were associated with one or more PIMs. The five most common PIMs were promethazine, ketorolac, propoxyphene, meperidine, and diphenhydramine. The total number of medications prescribed or administered during the ED visit was most strongly associated with PIM use. Other covariates associated with PIM use included rural location outside of the Northeast, being seen by a staff physician only (and not by a resident or intern), presenting with an injury, and the combination of female sex and age 65-74 years. There was a small but significant decrease in the proportion of visits associated with a PIM over the study period.
CONCLUSIONS: Potentially inappropriate medication administration in the ED remains common. Given rising concerns about preventable complications of medical care, this area may be of high priority for intervention. Substantial regional and hospital type (teaching versus nonteaching) variability appears to exist. Copyright (c) 2010 by the Society for Academic Emergency Medicine.

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Year:  2010        PMID: 20370754     DOI: 10.1111/j.1553-2712.2010.00667.x

Source DB:  PubMed          Journal:  Acad Emerg Med        ISSN: 1069-6563            Impact factor:   3.451


  14 in total

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2.  Effect of hospitalization on inappropriate prescribing in elderly Medicare beneficiaries.

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Review 3.  Year in review: medication mishaps in the elderly.

Authors:  Emily P Peron; Zachary A Marcum; Richard Boyce; Joseph T Hanlon; Steven M Handler
Journal:  Am J Geriatr Pharmacother       Date:  2011-02

4.  Inappropriate medication in a national sample of US elderly patients receiving home health care.

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Journal:  J Gen Intern Med       Date:  2012-03       Impact factor: 5.128

Review 5.  Determinants of Potentially Inappropriate Medication Use in Long-Term and Acute Care Settings: A Systematic Review.

Authors:  Stephanie K Nothelle; Ritu Sharma; Allison H Oakes; Madeline Jackson; Jodi B Segal
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6.  An Interdisciplinary Academic Detailing Approach to Decrease Inappropriate Medication Prescribing by Physician Residents for Older Veterans Treated in the Emergency Department.

Authors:  Jason M Moss; William E Bryan; Loren M Wilkerson; Heather A King; George L Jackson; Ryan K Owenby; Courtney H Van Houtven; Melissa B Stevens; James Powers; Camille P Vaughan; William W Hung; Ula Hwang; Alayne D Markland; Richard Sloane; William Knaack; Susan Nicole Hastings
Journal:  J Pharm Pract       Date:  2017-12-25

7.  Emergency department utilization by older adults: a descriptive study.

Authors:  Lesley P Latham; Stacy Ackroyd-Stolarz
Journal:  Can Geriatr J       Date:  2014-12-02

8.  Frequency of inappropriate medication prescription in hospitalized elderly patients in Italy.

Authors:  Francesco Napolitano; Maria Teresa Izzo; Gabriella Di Giuseppe; Italo F Angelillo
Journal:  PLoS One       Date:  2013-12-12       Impact factor: 3.240

Review 9.  Prescriber barriers and enablers to minimising potentially inappropriate medications in adults: a systematic review and thematic synthesis.

Authors:  Kristen Anderson; Danielle Stowasser; Christopher Freeman; Ian Scott
Journal:  BMJ Open       Date:  2014-12-08       Impact factor: 2.692

10.  Prescription of potentially inappropriate medications among older people with intellectual disability: a register study.

Authors:  Anna Axmon; Magnus Sandberg; Gerd Ahlström; Patrik Midlöv
Journal:  BMC Pharmacol Toxicol       Date:  2017-10-25       Impact factor: 2.483

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