Literature DB >> 20370365

Loss of in vitro resistance in Candida glabrata following discontinuation of fluconazole prophylaxis in a hematopoietic stem cell transplantation patient.

Steven D Westbrook1, Nathan P Wiederhold, Ana C Vallor, Susann Kotara, Stella Bernardo, Samuel A Lee, William R Kirkpatrick, Juan J Toro, Cesaro Freytes, Thomas F Patterson, Spencer W Redding.   

Abstract

We report a case of fluconazole-resistant oropharyngeal colonization caused by a strain of Candida glabrata that rapidly regained susceptibility once prophylaxis with this agent was discontinued and echinocandin therapy was initiated. Isolates collected before and after discontinuation of fluconazole were confirmed to be isogenic by RAPD analysis. Transcription analysis demonstrated constitutive expression of genes encoding efflux pumps in the isolate recovered on fluconazole prophylaxis and transient expression in those isolates collected after fluconazole was discontinued.

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Year:  2010        PMID： 20370365      PMCID： PMC2856480          DOI： 10.3109/13693780903213504

Source DB:  PubMed          Journal:  Med Mycol        ISSN： 1369-3786            Impact factor:   4.076


  8 in total

1.  Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method.

Authors:  K J Livak; T D Schmittgen
Journal:  Methods       Date:  2001-12       Impact factor: 3.608

2.  Candida glabrata PDR1, a transcriptional regulator of a pleiotropic drug resistance network, mediates azole resistance in clinical isolates and petite mutants.

Authors:  Huei-Fung Tsai; Anna A Krol; Kelly E Sarti; John E Bennett
Journal:  Antimicrob Agents Chemother       Date:  2006-04       Impact factor: 5.191

3.  Simple method for detecting fluconazole-resistant yeasts with chromogenic agar.

Authors:  T F Patterson; S G Revankar; W R Kirkpatrick; O Dib; A W Fothergill; S W Redding; D A Sutton; M G Rinaldi
Journal:  J Clin Microbiol       Date:  1996-07       Impact factor: 5.948

4.  Molecular genotyping of Candida species with special respect to Candida (Torulopsis) glabrata strains by arbitrarily primed PCR.

Authors:  K Becker; D Badehorn; S Deiwick; G Peters; W Fegeler
Journal:  J Med Microbiol       Date:  2000-06       Impact factor: 2.472

5.  Comparative evaluation of macrodilution and chromogenic agar screening for determining fluconazole susceptibility of Candida albicans.

Authors:  T F Patterson; W R Kirkpatrick; S G Revankar; R K McAtee; A W Fothergill; D I McCarthy; M G Rinaldi
Journal:  J Clin Microbiol       Date:  1996-12       Impact factor: 5.948

Review 6.  Candida glabrata: review of epidemiology, pathogenesis, and clinical disease with comparison to C. albicans.

Authors:  P L Fidel; J A Vazquez; J D Sobel
Journal:  Clin Microbiol Rev       Date:  1999-01       Impact factor: 26.132

7.  Identification of Candida spp. by randomly amplified polymorphic DNA analysis and differentiation between Candida albicans and Candida dubliniensis by direct PCR methods.

Authors:  Consuelo Bautista-Muñoz; Xavier M Boldo; Lourdes Villa-Tanaca; César Hernández-Rodríguez
Journal:  J Clin Microbiol       Date:  2003-01       Impact factor: 5.948

8.  Results from the ARTEMIS DISK Global Antifungal Surveillance study, 1997 to 2005: an 8.5-year analysis of susceptibilities of Candida species and other yeast species to fluconazole and voriconazole determined by CLSI standardized disk diffusion testing.

Authors:  M A Pfaller; D J Diekema; D L Gibbs; V A Newell; J F Meis; I M Gould; W Fu; A L Colombo; E Rodriguez-Noriega
Journal:  J Clin Microbiol       Date:  2007-04-18       Impact factor: 5.948
  8 in total
  3 in total

1.  Development of resistance of mutans streptococci and Porphyromonas gingivalis to chlorhexidine digluconate and amine fluoride/stannous fluoride-containing mouthrinses, in vitro.

Authors:  Eva M Kulik; Tuomas Waltimo; Roland Weiger; Irene Schweizer; Krystyna Lenkeit; Elisabeth Filipuzzi-Jenny; Clemens Walter
Journal:  Clin Oral Investig       Date:  2014-12-09       Impact factor: 3.573

2.  Microbiology and epidemiology of oral yeast colonization in hemopoietic progenitor cell transplant recipients.

Authors:  Steven D Westbrook; William R Kirkpatrick; Nathan P Wiederhold; Cesar O Freytes; Juan J Toro; Thomas F Patterson; Spencer W Redding
Journal:  Oral Surg Oral Med Oral Pathol Oral Radiol       Date:  2013-01-09

3.  Epidemiology and treatment approaches in management of invasive fungal infections.

Authors:  Jane Kriengkauykiat; James I Ito; Sanjeet S Dadwal
Journal:  Clin Epidemiol       Date:  2011-05-19       Impact factor: 4.790
  3 in total

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