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Literature DB >> 20368367

Have tumor suppressor PDCD4 and its counteragent oncogenic miR-21 gone rogue?

Matthew R Young¹, Arti N Santhanam, Noriko Yoshikawa, Nancy H Colburn.

Abstract

Entities: Disease Gene

Mesh：

Substances：

Year: 2010 PMID： 20368367 PMCID： PMC2895370 DOI： 10.1124/mi.10.2.5

Source DB: PubMed Journal: Mol Interv ISSN： 1534-0384

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27 in total

1. Programmed cell death 4 (PDCD4) is an important functional target of the microRNA miR-21 in breast cancer cells.

Authors: Lisa B Frankel; Nanna R Christoffersen; Anders Jacobsen; Morten Lindow; Anders Krogh; Anders H Lund
Journal: J Biol Chem Date: 2007-11-08 Impact factor: 5.157

2. Translation inhibitor Pdcd4 is targeted for degradation during tumor promotion.

Authors: Tobias Schmid; Aaron P Jansen; Alyson R Baker; Glenn Hegamyer; John P Hagan; Nancy H Colburn
Journal: Cancer Res Date: 2008-02-22 Impact factor: 12.701

Review 3. The tumour suppressor Pdcd4: recent advances in the elucidation of function and regulation.

Authors: Brigitte Lankat-Buttgereit; Rüdiger Göke
Journal: Biol Cell Date: 2009-06 Impact factor: 4.458

Review 4. MicroRNAs in Cancer.

Authors: Ramiro Garzon; George A Calin; Carlo M Croce
Journal: Annu Rev Med Date: 2009 Impact factor: 13.739

5. MicroRNA-21 (miR-21) post-transcriptionally downregulates tumor suppressor Pdcd4 and stimulates invasion, intravasation and metastasis in colorectal cancer.

Authors: I A Asangani; S A K Rasheed; D A Nikolova; J H Leupold; N H Colburn; S Post; H Allgayer
Journal: Oncogene Date: 2007-10-29 Impact factor: 9.867

6. MicroRNA-21 promotes cell transformation by targeting the programmed cell death 4 gene.

Authors: Z Lu; M Liu; V Stribinskis; C M Klinge; K S Ramos; N H Colburn; Y Li
Journal: Oncogene Date: 2008-03-31 Impact factor: 9.867

7. MicroRNA-21 protects against the H(2)O(2)-induced injury on cardiac myocytes via its target gene PDCD4.

Authors: Yunhui Cheng; Xiaojun Liu; Shuo Zhang; Ying Lin; Jian Yang; Chunxiang Zhang
Journal: J Mol Cell Cardiol Date: 2009-01-27 Impact factor: 5.000

8. Loss of programmed cell death 4 expression marks adenoma-carcinoma transition, correlates inversely with phosphorylated protein kinase B, and is an independent prognostic factor in resected colorectal cancer.

Authors: Giridhar Mudduluru; Fabian Medved; Rainer Grobholz; Camela Jost; Anette Gruber; Joerg H Leupold; Stefan Post; Aaron Jansen; Nancy H Colburn; Heike Allgayer
Journal: Cancer Date: 2007-10-15 Impact factor: 6.860

9. An autoregulatory loop mediated by miR-21 and PDCD4 controls the AP-1 activity in RAS transformation.

Authors: F Talotta; A Cimmino; M R Matarazzo; L Casalino; G De Vita; M D'Esposito; R Di Lauro; P Verde
Journal: Oncogene Date: 2008-10-13 Impact factor: 9.867

Review 10. miR-21: a small multi-faceted RNA.

Authors: Anna M Krichevsky; Galina Gabriely
Journal: J Cell Mol Med Date: 2009-01 Impact factor: 5.310

26 in total

1. Loss of programmed cell death 4 induces apoptosis by promoting the translation of procaspase-3 mRNA.

Authors: K Eto; S Goto; W Nakashima; Y Ura; S-I Abe
Journal: Cell Death Differ Date: 2011-09-30 Impact factor: 15.828

2. Role of microRNA-21 and programmed cell death 4 in the pathogenesis of human uterine leiomyomas.

Authors: J Browning Fitzgerald; Vargheese Chennathukuzhi; Faezeh Koohestani; Romana A Nowak; Lane K Christenson
Journal: Fertil Steril Date: 2012-06-22 Impact factor: 7.329

3. Involvement of androgen receptor (AR)/microRNA-21 axis in hypoxia/reoxygenation-induced apoptosis of mouse renal tubular epithelial cells.

Authors: Tongchang Chen; Qiu Yao; Weichao Wang; Zhenfeng Ye; Yawei Huang; Meng Wu; Xiaoqing Xi
Journal: Am J Transl Res Date: 2019-09-15 Impact factor: 4.060

Have tumor suppressor PDCD4 and its counteragent oncogenic miR-21 gone rogue?

1. Programmed cell death 4 (PDCD4) is an important functional target of the microRNA miR-21 in breast cancer cells.

2. Translation inhibitor Pdcd4 is targeted for degradation during tumor promotion.

Review 3. The tumour suppressor Pdcd4: recent advances in the elucidation of function and regulation.

Review 4. MicroRNAs in Cancer.

5. MicroRNA-21 (miR-21) post-transcriptionally downregulates tumor suppressor Pdcd4 and stimulates invasion, intravasation and metastasis in colorectal cancer.

6. MicroRNA-21 promotes cell transformation by targeting the programmed cell death 4 gene.

7. MicroRNA-21 protects against the H(2)O(2)-induced injury on cardiac myocytes via its target gene PDCD4.

8. Loss of programmed cell death 4 expression marks adenoma-carcinoma transition, correlates inversely with phosphorylated protein kinase B, and is an independent prognostic factor in resected colorectal cancer.

9. An autoregulatory loop mediated by miR-21 and PDCD4 controls the AP-1 activity in RAS transformation.

Review 10. miR-21: a small multi-faceted RNA.

1. Loss of programmed cell death 4 induces apoptosis by promoting the translation of procaspase-3 mRNA.

2. Role of microRNA-21 and programmed cell death 4 in the pathogenesis of human uterine leiomyomas.

3. Involvement of androgen receptor (AR)/microRNA-21 axis in hypoxia/reoxygenation-induced apoptosis of mouse renal tubular epithelial cells.

4. An essential role of PDCD4 in progression and malignant proliferation of gastrointestinal stromal tumors.

5. Cytoplasmic localization of programmed cell death 4 contributes to its anti-apoptotic function.

6. Berberine regulates the microRNA-21-ITGΒ4-PDCD4 axis and inhibits colon cancer viability.

7. Epigenetic changes associated with inflammation in breast cancer patients treated with chemotherapy.

8. Anti-inflammatory effects of miR-21 in the macrophage response to peritonitis.

9. MiR-21 Suppresses Anoikis through Targeting PDCD4 and PTEN in Human Esophageal Adenocarcinoma.

10. PDCD4 expression in thyroid neoplasia.