| Literature DB >> 20365007 |
K I Mazzitello1, C M Arizmendi, F Family, H E Grossniklaus.
Abstract
The kinetics of lipofuscin growth in diseased retinal pigment epithelium cells is investigated using Monte Carlo simulations and scaling theory on a cluster aggregation model. The model captures the essential physics of lipofuscin growth in the cells. A remarkable feature is that small particles may be removed from the cells while the larger ones become fixed and grow by aggregation. Model simulations are compared to the number of lipofuscin granules in eyes with early age-related degeneration.Entities:
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Year: 2009 PMID： 20365007 PMCID： PMC2993693 DOI： 10.1103/PhysRevE.80.051908
Source DB: PubMed Journal: Phys Rev E Stat Nonlin Soft Matter Phys ISSN： 1539-3755